Evidence map›Paper›PMID 39384865›Full record

ArticleScientific reports2024

Copper nanoparticles biosynthesis by Priestia megaterium and its application as antibacterial and antitumor agents.

Salma H Mohamed, Badawi A Othman, Basma T Abd-Elhalim, Mohammed N Abou Seada

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Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Salma H MohamedDepartment of Agricultural Microbiology, Faculty of Agriculture, Ain Shams University, Hadayek Shoubra, PO Box 68, Cairo, 11241, Egypt.ORCID http://orcid.org/0009-0003-3086-4096
Badawi A OthmanDepartment of Agricultural Microbiology, Faculty of Agriculture, Ain Shams University, Hadayek Shoubra, PO Box 68, Cairo, 11241, Egypt.
Basma T Abd-ElhalimDepartment of Agricultural Microbiology, Faculty of Agriculture, Ain Shams University, Hadayek Shoubra, PO Box 68, Cairo, 11241, Egypt. basma.talaat@agr.asu.edu.eg.ORCID http://orcid.org/0000-0002-3009-332X
Mohammed N Abou SeadaDepartment of Agricultural Microbiology, Faculty of Agriculture, Ain Shams University, Hadayek Shoubra, PO Box 68, Cairo, 11241, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growth of material science and technology places high importance on creating better processes for synthesizing copper nanoparticles. Thus, an easy, ecological, and benign process for producing copper nanoparticles (CuNPs) has been developed using Priestia sp. bacteria utilizing a variety of low-cost agro-industrial wastes and byproducts. The biosynthesis of CuNPs was conducted using glucose medium and copper ions salt solution, then it was replaced by utilizing low-cost agro-industrial wastes. UV-visible spectroscopy, dynamic light scattering (DLS), X-ray diffraction (XRD), High-resolution transmission electron microscope (HR-TEM), Attenuated Total Reflectance and Fourier transform infrared (ATR-FTIR), and zeta potential were used to characterize the biosynthesized CuNPs. The cytotoxicity of CuNPs using Vero -CCL-81 cell lines, and antibacterial and antitumor properties using human colon epithelial colorectal adenocarcinoma Caco-2-HTB-37 cell lines were assessed. The UV-visible and DLS studies revealed CuNPs formation, with a maximum concentration of 6.19 ppm after 48 h, as indicated by a 0.58 Surface plasmon resonance (SPR) within 450 nm and 57.73 nm particle size. The 16S rRNA gene analysis revealed that Priestia sp. isolate is closely related to Priestia megaterium and has been deposited in the NCBI GenBank with accession number AMD 2024. The biosynthesis with various agro-industrial wastes indicated blackstrap sugar cane molasses being the most effective for reducing CuNPs size to 3.12 nm owing to various reducing and stabilizing active compounds. The CuNPs were free of contaminants, with a sphere-shaped structure and a cytotoxicity assessment with an IC

Indexed as

Anti-Bacterial AgentsAntineoplastic AgentsCopperMetal NanoparticlesActinobacteriaAnimalsCaco-2 CellsChlorocebus aethiopsHumansMicrobial Sensitivity TestsVero CellsAnti-Bacterial AgentsAntineoplastic AgentsCopperAgro-industrial wastesAntibacterial effectAntitumor activityCaco-2-HTB-37 cell lineCopper nanoparticlesCytotoxicity activityPriestia megaterium

Identifiers

PMID39384865
PMCPMC11464900

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