ArticleCanadian journal of anaesthesia = Journal canadien d'anesthesie2024
Environmental impact of intravenous versus oral administration materials for acetaminophen and ketoprofen in a French university hospital: an eco-audit study using a life cycle analysis.
Article in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Choosing Wisely Canada climate-conscious recommendations for critical care medicine.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2026Article
- Environmental benefits of switching from intravenous to oral administration of ciprofloxacin.The Journal of antimicrobial chemotherapy · 2026Article
- Sustainable Intensive Care: Do Not Forget IV to Oral Switch!Critical care medicine · 2026Article
- Applying Abstract Text Mining as a Complement to PRISMA in Reviewing the Scope of Healthcare's Circular Economy Comment on "A Review of the Applicability of Current Green Practices in Healthcare Facilities".International journal of health policy and management · 2026Article
- Contribution of hospitals and clinical services to global warming: a scoping systematic review.Frontiers in public health · 2026Article
- Article
- PO-llution control: a cross-sectional study on the role of antimicrobial stewardship in reducing healthcare's carbon footprint.JAC-antimicrobial resistance · 2025Article
- In reply: Comment on: Environmental impact of intravenous versus oral administration materials for acetaminophen and ketoprofen in a French university hospital: an eco-audit study using life cycle analysis.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2025Article
- Comment on: Environmental impact of intravenous versus oral administration materials for acetaminophen and ketoprofen in a French university hospital: an eco-audit study using life cycle analysis.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2025Article
- It is time to consider the climate crisis in haematology.Clinical hematology international · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeThe combination of acetaminophen with a nonsteroidal anti-inflammatory drug is the cornerstone of perioperative multimodal analgesia. These drugs can be administered intravenously or orally as premedication, consistent with the concept of pre-emptive and preventive analgesia. We aimed to assess the environmental impact of their intravenous and oral administration in a French university hospital.
methodsWe carried out a life cycle assessment to determine the amount of greenhouse gas emissions and depletion of water resources resulting from the oral vs intravenous administration of 1 g acetaminophen and 50 mg ketoprofen. We assessed two schemes of intravenous administration, depending on the use of the same or a different infusion set for each drug.
resultsAt our centre, the intravenous administration of both drugs was associated with the emission of 444-556 g CO
conclusionThis eco-audit indicates that oral administration of acetaminophen and ketoprofen results in significantly lower carbon emissions and water consumption than intravenous administration. These findings highlight the importance of using the oral route for most patients, limiting intravenous administration for those with specific needs because of higher environmental impact and cost.
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