Evidence map›Paper›PMID 39384700›Full record

Observational studyJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2025

Fluoroscopy-free cardioneuroablation for functional bradycardia: a single-center experience.

Parnia Abolhassan Choubdar, Megan Gruber, Jose Carlos Pachon-M, Stephen Manu, Mansour Razminia, John Clark

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Older age is not an independent predictor of syncope recurrence following cardioneuroablation for reflex syncope.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Observational
  3. Diagnostic yield of nitroglycerin-potentiated head-up tilt test in a pediatric population with suspected reflex syncope.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Parnia Abolhassan ChoubdarDepartment of Medicine, University of Kentucky, Bowling Green, KY, USA. parniachoub@gmail.com.ORCID http://orcid.org/0000-0001-7402-6121
Megan GruberDepartment of Cardiovascular Disease, Metrohealth Medical Center, Cleveland, OH, USA.
Jose Carlos Pachon-MDepartment of Cardiovascular Disease, Heart Hospital, São Paulo, Brazil.
Stephen ManuDepartment of Pediatric Cardiology, Akron Children's Hospital, Akron, OH, USA.
Mansour RazminiaDepartment of Cardiac Electrophysiology, St. Joseph Hospital, Elgin, IL, USA.
John ClarkDepartment of Pediatric Cardiology, Akron Children's Hospital, Akron, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardioneuroablation (CNA) is an emerging treatment for cardioinhibitory syncope and functional AV block. This study aimed to evaluate the safety and efficacy of a fluoroless CNA approach using three-dimensional mapping and extracardiac vagal stimulation (ECVS).

methodsThis prospective observational study included 22 patients (mean age 21 years) with clinically significant functional bradycardia who underwent fluoroless CNA. Procedural success was defined as elimination or significant attenuation of the vagal response to ECVS.

resultsCNA was successfully performed in all patients with a mean procedure time of 251 min. Fluoroscopy was avoided in 91% of cases. At a mean follow-up of 11.4 months, 77% of patients remained symptom-free. Among pacemaker patients, 90% did not require further pacing, and 6/10 (60%) have had their pacemakers turned off. No complications were seen during the procedure.

conclusionsFluoroscopy-free CNA is a safe and effective treatment for functional bradycardia, offering high procedural success rates and favorable symptom-free outcomes while minimizing radiation exposure.

Indexed as

BradycardiaCatheter AblationAdolescentAdultFemaleFluoroscopyHumansImaging, Three-DimensionalMaleProspective StudiesTreatment OutcomeYoung AdultCardioinhibitionCardioneuroablationFluoroscopyRadiationVasovagal syncope

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.