Evidence map›Paper›PMID 39384696›Full record

ArticleJournal of the International AIDS Society2024

Are social protection and food security accelerators for adolescents to achieve the Global AIDS targets?

Lucie Cluver, Siyanai Zhou, Olanrewaju Edun, Allison Oman Lawi, Nontokozo Langwenya, David Chipanta, Gayle Sherman, Lorraine Sherr, Mona Ibrahim, Rachel Yates and 2 more

Abstract read
In one paragraph

Article in Journal of the International AIDS Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lucie Cluver *Department of Social Policy and Intervention, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-0418-835X
Siyanai Zhou *Centre for Social Science Research, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-6525-1244
Olanrewaju EdunMRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, UK.ORCID https://orcid.org/0000-0002-0306-5171
Allison Oman LawiNutrition Division, United Nations World Food Programme, Rome, Italy.
Nontokozo LangwenyaDepartment of Social Policy and Intervention, University of Oxford, Oxford, UK.
David ChipantaUNAIDS, Windhoek, Namibia.
Gayle ShermanCentre for HIV and STIs, National Institute for Communicable Diseases, Johannesburg, South Africa.
Lorraine SherrHealth Psychology Unit, Institute of Global Health, University College London, London, UK.
Mona IbrahimDepartment of Social Policy and Intervention, University of Oxford, Oxford, UK.
Rachel YatesDepartment of Social Policy and Intervention, University of Oxford, Oxford, UK.
Louise GordonDepartment of Social Policy and Intervention, University of Oxford, Oxford, UK.
Elona ToskaDepartment of Social Policy and Intervention, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-3800-3173

Funding

Undetectable and Untransmittable: reducing HIV transmission among young women living with HIV, their partners and children in South AfricaK43TW011434 · FIC · UNIVERSITY OF CAPE TOWN · PI TOSKA, ELONA · 2019 to 2023
$720k
Accelerating Achievement for Africa's Adolescents (Accelerate) Hub ES/S008101/1CIPHERClaude Leon Foundation 08 559/CEuropean Union's (EU) Seventh Framework Programme FP7/2007-2013EU's Horizon 2020 research and innovation programme/ERC 737476EU's Horizon 2020 research and innovation programme/ERC 771468Evidence for HIV Prevention in Southern AfricaFIC NIH HHS K43 TW011434John Fell Fund 103/757John Fell Fund 161/033Leverhulme Trust PLP-2014-095National Institute on Mental HealthNational Institutes of Health Research MR/R022372/1|NIH HHS K43TW011434Nuffield Foundation CPF/41513Oak Foundation OFIL-20-057Oak Foundation R46194/AA001Research EnglandSwedish International Development Agency, 2gether 4 SRHR Programmethe European Research CouncilUK Department for International Development (DFID)UK Medical Research CouncilUK Research and Innovation Global Challenges Research FundUNICEF's Eastern and Southern Africa OfficeUniversity of Oxford's Economic and Social Research Council Impact Acceleration Account 1602-KEA-189University of Oxford's Economic and Social Research Council Impact Acceleration Account IAA-MT13-003University of Oxford's Economic and Social Research Council Impact Acceleration Account K1311-KEA-004
6 · The paper itself

Abstract

introductionWithout effective, scalable interventions, we will fail to achieve the Global AIDS Targets of zero AIDS-related deaths, zero HIV transmission and zero discrimination. This study examines associations of social protection and food security among adolescents living with HIV (ALHIV), with three Global AIDS Targets aligned outcomes: antiretroviral treatment (ART) adherence and viral suppression, HIV transmission risk behaviour and enacted stigma.

methodsWe conducted three study visits over 2014-2018 with 1046 ALHIV in South Africa's Eastern Cape province. Standardized surveys provided information on receipt of government-provided cash transfers and past-week food security, alongside self-reported ART adherence, sexual debut and condom use, and enacted HIV-related stigma. Viral load (VL) data was obtained through data extraction from patient files and linkage with National Health Laboratory Service test results (2014-2020). We used a multivariable random-effects regression model to estimate associations between receiving government cash transfers and food security and three outcomes: ART adherence and viral suppression, delayed sexual debut or consistent condom use and no enacted stigma. We tested moderation by sex and age and fitted disaggregated models for each outcome.

resultsAmong the 933 ALHIV completing all three study visits, 55% were female, and the mean age was 13.6 years at baseline. Household receipt of a government cash transfer was associated with improvements on all outcomes: ART adherence and viral suppression (aOR 2.03, 95% CI 1.29-3.19), delayed sexual debut or consistent condom use (aOR 1.62, 95% CI 1.16-2.27) and no enacted stigma (aOR 2.33, 95% CI 1.39-3.89). Food security was associated with improvements on all outcomes: ART adherence and viral suppression (aOR 1.73, 95% CI 1.30-2.30), delayed sexual debut or consistent condom use (aOR 1.30, 95% CI 1.03-1.64) and no enacted stigma (aOR 1.91, 95% CI 1.32-2.76). Receiving both cash transfers and food security increased the probability of ART adherence and VL suppression from 36% to 60%; delayed sexual debut or consistent condom use from 67% to 81%; and no enacted stigma from 84% to 96%.

conclusionsGovernment-provided cash transfers and food security, individually and in combination, are associated with improved outcomes for ALHIV aligned with Global AIDS Targets. They may be important, and underutilized, accelerators for achieving these targets.

Indexed as

Food SecurityHIV InfectionsSocial StigmaAcquired Immunodeficiency SyndromeAdolescentDrug MonitoringFemaleHumansMaleSouth AfricaViral LoadYoung AdultadolescentsHIV preventionpreventionsocial protectionstigmatreatment

Identifiers

PMID39384696
PMCPMC11464211

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.