Evidence map›Paper›PMID 39384575›Full record

SynthesisEuropean heart journal. Quality of care & clinical outcomes2025

Standardized and hierarchically classified heart failure and complementary disease monitoring outcome measures: European Unified Registries for Heart Care Evaluation and Randomised Trials (EuroHeart).

Asad Bhatty, Chris Wilkinson, Gorav Batra, Suleman Aktaa, Adam B Smith, Ali Wahab, Sam Chappell, Joakim Alfredsson, David Erlinge, Jorge Ferreira and 20 more

Abstract readSystematic Review
In one paragraph

Synthesis in European heart journal. Quality of care & clinical outcomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Asad BhattyLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.ORCID 0009-0003-3254-9508
Chris WilkinsonHull York Medical School, University of York, York, UK.ORCID 0000-0003-0748-0150
Gorav BatraDepartment of Medical Sciences, Cardiology and Uppsala Clinical Research Centre, Uppsala University, Uppsala, Sweden.ORCID 0000-0002-2480-9547
Suleman AktaaLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Adam B SmithLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Ali WahabLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.ORCID 0009-0001-6245-6260
Sam ChappellLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Joakim AlfredssonLinköping University Hospital, Linköping, Sweden.ORCID 0000-0002-1415-7178
David ErlingeLund University, Sweden.
Jorge FerreiraHospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Portugal.
Ingibjörg J GuðmundsdóttirDepartment of Cardiology, Landspitali University Hospital, Reykjavik, Iceland.
Þórdís Jóna HrafnkelsdóttirDepartment of Cardiology, Landspitali University Hospital, Reykjavik, Iceland.
Inga Jóna IngimarsdóttirDepartment of Cardiology, Landspitali University Hospital, Reykjavik, Iceland.
Alar IrsTartu University Hospital, Estonia.
András JánosiGyörgy Gottsegen National Cardiovascular Institute, Hungary.
Zoltán JáraiSouth Buda Center Hospital, Szent Imre Teaching Hospital, Hungary.
Manuel Oliveira-SantosCardiology Department, Unidade Local de Saúde de Coimbra, Portugal.
Bogdan A PopescuUniversity of Medicine and Pharmacy Carol Davila, Emergency Institute for Cardiovascular Diseases, Bucharest, Romania.ORCID 0000-0001-6122-8533
Peter VaskoLinköping University Hospital, Linköping, Sweden.
Dragos VinereanuUniversity of Medicine and Pharmacy Carol Davila, Emergency Institute for Cardiovascular Diseases, Bucharest, Romania.
Jonathan YapNational Heart Centre Singapore, Singapore.
Raffaele BugiardiniANMCO Research Centre, Heart Care Foundation, 50121 Florence, Italy.ORCID 0000-0002-6819-6818
Edina CenkoANMCO Research Centre, Heart Care Foundation, 50121 Florence, Italy.ORCID 0000-0001-8102-3324
Ramesh NadarajahLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.ORCID 0000-0001-9895-9356
Matthew R SydesMRC Clinical Trials Unit at UCL, University College London, London, UK.
Stefan JamesDepartment of Medical Sciences, Cardiology and Uppsala Clinical Research Centre, Uppsala University, Uppsala, Sweden.ORCID 0000-0003-4413-9736
Aldo P MaggioniANMCO Research Centre, Heart Care Foundation, 50121 Florence, Italy.
Lars WallentinDepartment of Medical Sciences, Cardiology and Uppsala Clinical Research Centre, Uppsala University, Uppsala, Sweden.ORCID 0000-0003-0378-6531
Barbara CasadeiDivision of Cardiovascular Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford.ORCID 0000-0002-6801-1617
Chris P GaleLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe lack of standardized definitions for heart failure outcome measures limits the ability to reliably assess the effectiveness of heart failure therapies. The European Unified Registries for Heart Care Evaluation and Randomised Trials (EuroHeart) aimed to produce a catalogue of internationally endorsed data definitions for heart failure outcome measures. METHODS AND

resultsFollowing the EuroHeart methods for the development of cardiovascular data standards, a working group was formed of representatives from the European Society of Cardiology Heart Failure Association and other leading heart failure experts. A systematic review of observational and randomized clinical trials identified current outcome measures, which was supplemented by clinical practice guidelines and existing registries for contemporary definitions. A modified Delphi process was employed to gain consensus for variable inclusion and whether collection should be mandatory (Level 1) or optional (Level 2) within EuroHeart. In addition, a set of complementary outcome measures were identified by the working group as of scientific and clinical importance for longitudinal monitoring for people with heart failure. Five Level 1 and two Level 2 outcome measures were selected and defined, alongside five complementary monitoring outcomes for patients with heart failure.

conclusionWe present a structured, hierarchical catalogue of internationally endorsed heart failure outcome measures. This will facilitate quality improvement, high quality observational research, registry-based trials, and post-market surveillance of medical devices.

Indexed as

Heart FailureOutcome Assessment, Health CareRandomized Controlled Trials as TopicRegistriesEuropeHumansEuroHeartHeart failureOutcomes definitionsQuality of care

Identifiers

PMID39384575
PMCPMC12587276

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.