Evidence map›Paper›PMID 39384406›Full record

ArticlePhotochemistry and photobiology

Prodrugs of paclitaxel improve in situ photo-vaccination.

Prabhanjan Giram, Ganesh Bist, Sukyung Woo, Elizabeth Wohlfert, Roberto Pili, Youngjae You

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Photochemistry and photobiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Prabhanjan GiramDepartment of Pharmaceutical Sciences, University at Buffalo, The State University of New York, Buffalo, New York, USA.
Ganesh BistDepartment of Pharmaceutical Sciences, University at Buffalo, The State University of New York, Buffalo, New York, USA.
Sukyung WooDepartment of Pharmaceutical Sciences, University at Buffalo, The State University of New York, Buffalo, New York, USA.
Elizabeth WohlfertDepartment of Microbiology and Immunology, University at Buffalo School of Medicine, Buffalo, New York, USA.
Roberto PiliDivision of Hematology and Oncology, Department of Medicine, University at Buffalo, Buffalo, New York, USA.
Youngjae YouDepartment of Pharmaceutical Sciences, University at Buffalo, The State University of New York, Buffalo, New York, USA.ORCID 0000-0003-0835-464X

Funding

Site Specific Drug Delivery with Light-responsive Conjugates for Photo-biomodulationR01GM113940 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Youngjae You · 2015 to 2026
$3.0M
NIGMS NIH HHS R01 GM113940NIH HHS R01GM113940
6 · The paper itself

Abstract

Photodynamic therapy (PDT) effectively kills cancer cells and initiates immune responses that promote anticancer effects locally and systemically. Primarily developed for local and regional cancers, the potential of PDT for systemic antitumor effects [in situ photo-vaccination (ISPV)] remains underexplored. This study investigates: (1) the comparative effectiveness of paclitaxel (PTX) prodrug [Pc-(L-PTX)

Indexed as

PaclitaxelPhotochemotherapyProdrugsAnimalsCell Line, TumorFemaleMiceMice, Inbred BALB CPaclitaxelProdrugsa‐CTLA‐4CD8+ T cellscheck point blockade inhibitorsimmunotherapyin situ photo‐vaccinationneutrophilspaclitaxel prodrugphotodynamic therapysystemic antitumor effect

Identifiers

PMID39384406
PMCPMC11978925

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.