ArticleOpen heart2024
Association between kidney function, frailty and receipt of invasive management after acute coronary syndrome.
Article in Open heart, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03507309 (National Institute for Health Research), which is not on this map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
National Institute for Health Research (NIHR) Cardiovascular Health Informatics Collaborative
Who cites it
4 citing papers in PubMed.
- Frailty Transforms Care Continuity-Mortality Relationships Across Age Groups: Evidence From Taiwan and South Korea.Journal of cachexia, sarcopenia and muscle · 2026Article
- How are treatment decisions for myocardial infarction made in the presence of advanced kidney disease? A qualitative study in the UK.BMJ open · 2025Article
- Frailty-stratified effectiveness of SGLT2 inhibitors versus DPP-4 inhibitors and GLP-1 receptor agonists on pulmonary outcomes in type 2 diabetes: a nationwide cohort study.EClinicalMedicine · 2025Article
- Acute coronary events in kidney patients: the dialysis dilemma.The British journal of cardiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors.
Funding
Abstract
backgroundReduced estimated glomerular filtration rate (eGFR) is associated with lower use of invasive management and increased mortality after acute coronary syndrome (ACS). The reasons for this are unclear.
methodsA retrospective clinical cohort study was performed using data from the English National Institute for Health Research Health Informatics Collaborative (2010-2017). Multivariable logistic regression was used to investigate whether eGFR<90 mL/min/1.73 m
resultsAmong 10 205 people with ACS, an eGFR of <60 mL/min/1.73m
conclusionsIn people with ACS, lower eGFR was associated with reduced receipt of invasive coronary management and increased mortality. Adjustment for frailty failed to change these observations. Further research is required to explain these disparities and determine whether treatment variation reflects optimal care for people with low eGFR. TRIAL REGISTRATION NUMBER: NCT03507309.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.