Evidence map›Paper›PMID 39384295›Full record

ArticleBMJ (Clinical research ed.)2024

Rainfall events and daily mortality across 645 global locations: two stage time series analysis.

Cheng He, Susanne Breitner-Busch, Veronika Huber, Kai Chen, Siqi Zhang, Antonio Gasparrini, Michelle Bell, Haidong Kan, Dominic Royé, Ben Armstrong and 48 more

Abstract read
In one paragraph

Article in BMJ (Clinical research ed.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

58 authors.

Cheng HeInstitute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany cheng.he@helmholtz-munich.de.ORCID 0000-0002-8470-0834
Susanne Breitner-BuschInstitute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.
Veronika HuberInstitute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.
Kai ChenDepartment of Environmental Health Sciences, Yale School of Public Health, New Haven, CT, USA.
Siqi ZhangDepartment of Environmental Health Sciences, Yale School of Public Health, New Haven, CT, USA.
Antonio GasparriniEnvironment and Health Modelling Lab, Department of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, London, UK.
Michelle BellSchool of the Environment, Yale University, New Haven, CT, USA.
Haidong KanDepartment of Environmental Health, School of Public Health, Fudan University, Shanghai, China.
Dominic RoyéClimate Research Foundation, CIBER of Epidemiology and Public Health, Madrid, Spain.
Ben ArmstrongDepartment of Public Health Environments and Society, London School of Hygiene and Tropical Medicine, London, UK.
Joel SchwartzDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Francesco SeraDepartment of Statistics, Computer Science and Applications "G Parenti," University of Florence, Florence, Italy.
Ana Maria Vicedo-CabreraInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.
Yasushi HondaCenter for Climate Change Adaptation, National Institute for Environmental Studies, Tsukuba, Japan.
Jouni J K JaakkolaCenter for Environmental and Respiratory Health Research, University of Oulu, Oulu, Finland.
Niilo RytiCenter for Environmental and Respiratory Health Research, University of Oulu, Oulu, Finland.
Jan KyselýInstitute of Atmospheric Physics, Czech Academy of Sciences, Prague, Czech Republic.
Yuming GuoSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
Shilu TongNational Institute of Environmental Health, Chinese Center for Disease Control and Prevention, Beijing, China.
Francesca de'DonatoDepartment of Epidemiology, Lazio Regional Health Service, ASL ROMA 1, Rome, Italy.
Paola MichelozziDepartment of Epidemiology, Lazio Regional Health Service, ASL ROMA 1, Rome, Italy.
Micheline de Sousa Zanotti Stagliorio CoelhoDepartment of Pathology, Faculty of Medicine, University of Sao Paulo, Sao Paulo, Brazil.
Paulo Hilario Nascimento SaldivaINSPER, Sao Paulo, Brazil.
Eric LavigneSchool of Epidemiology and Public Health, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada.
Hans OrruDepartment of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Ene IndermitteDepartment of Family Medicine and Public Health, University of Tartu, Tartu, Estonia.
Mathilde PascalDepartment of Environmental and Occupational Health, French National Public Health Agency, Saint Maurice, France.
Patrick GoodmanTechnological University Dublin, Dublin, Ireland.
Ariana ZekaInstitute for Global Health, University College London, UK.
Yoonhee KimDepartment of Global Environmental Health, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Magali Hurtado DiazDepartment of Environmental Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico.
Eunice Elizabeth Félix ArellanoDepartment of Environmental Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico.
Ala OvercencoNational Agency for Public Health of Ministry of Health, Labour and Social Protection of the Republic of Moldova, Chisinau, Republic of Moldova.
Jochem KlompmakerNational Institute for Public Health and the Environment (RIVM), Centre for Sustainability and Environmental Health, Bilthoven, Netherlands.
Shilpa RaoNorwegian institute of Public Health, Oslo, Norway.
Alfonso Diz-Lois PalomaresNorwegian institute of Public Health, Oslo, Norway.
Gabriel CarrascoInstitute of Tropical Medicine, Universidad Peruana Cayetano Heredia, Lima, Peru.
Xerxes SeposoSchool of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.
Susana das Neves Pereira da SilvaNational Institute of Health Dr Ricardo Jorge, Portugal.
Joana MadureiraNational Institute of Health Dr Ricardo Jorge, Portugal.
Iulian-Horia HolobacaFaculty of Geography, Babeș-Bolyai University, Cluj-Napoca, Romania.
Noah ScovronickGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Fiorella AcquaottaDepartment of Earth Sciences, University of Turin, Turin, Italy.
Ho KimGraduate School of Public Health, Seoul National University, Seoul, Republic of Korea.
Whanhee LeeSchool of Biomedical Convergence Engineering, College of Information and Biomedical Engineering, Pusan National University, Yangsan, Republic of Korea.
Masahiro HashizumeDepartment of Global Health Policy, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
Aurelio TobiasInstitute of Environmental Assessment and Water Research, Spanish Council for Scientific Research, Barcelona, Spain.
Carmen ÍñiguezDepartment of Statistics and Computational Research, University of Valencia, Valencia, Spain.
Bertil ForsbergDepartment of Public Health and Clinical Medicine, Umea University, Umea, Sweden.
Martina S RagettliSwiss Tropical and Public Health Institute, Allschwil, Switzerland.
Yue Leon GuoEnvironmental and Occupational Medicine, National Taiwan University (NTU) College of Medicine and NTU Hospital, Taipei, Taiwan.
Shih-Chun PanNational Institute of Environmental Health Science, National Health Research Institutes, Zhunan, Taiwan.
Samuel OsorioDepartment of Environmental Health, University of Sao Paulo, Sao Paulo, Brazil.
Shanshan LiSchool of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia.
Antonella ZanobettiDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Tran Ngoc DangInstitute of Research and Development, Duy Tan University, Da Nang, Vietnam.
Do Van DungDepartment of Environmental Health, Faculty of Public Health, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Alexandra SchneiderInstitute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the associations between characteristics of daily rainfall (intensity, duration, and frequency) and all cause, cardiovascular, and respiratory mortality.

designTwo stage time series analysis.

setting645 locations across 34 countries or regions. POPULATION: Daily mortality data, comprising a total of 109 954 744 all cause, 31 164 161 cardiovascular, and 11 817 278 respiratory deaths from 1980 to 2020.

main outcome measureAssociation between daily mortality and rainfall events with return periods (the expected average time between occurrences of an extreme event of a certain magnitude) of one year, two years, and five years, with a 14 day lag period. A continuous relative intensity index was used to generate intensity-response curves to estimate mortality risks at a global scale.

resultsDuring the study period, a total of 50 913 rainfall events with a one year return period, 8362 events with a two year return period, and 3301 events with a five year return period were identified. A day of extreme rainfall with a five year return period was significantly associated with increased daily all cause, cardiovascular, and respiratory mortality, with cumulative relative risks across 0-14 lag days of 1.08 (95% confidence interval 1.05 to 1.11), 1.05 (1.02 to 1.08), and 1.29 (1.19 to 1.39), respectively. Rainfall events with a two year return period were associated with respiratory mortality only, whereas no significant associations were found for events with a one year return period. Non-linear analysis revealed protective effects (relative risk <1) with moderate-heavy rainfall events, shifting to adverse effects (relative risk >1) with extreme intensities. Additionally, mortality risks from extreme rainfall events appeared to be modified by climate type, baseline variability in rainfall, and vegetation coverage, whereas the moderating effects of population density and income level were not significant. Locations with lower variability of baseline rainfall or scarce vegetation coverage showed higher risks.

conclusionDaily rainfall intensity is associated with varying health effects, with extreme events linked to an increasing relative risk for all cause, cardiovascular, and respiratory mortality. The observed associations varied with local climate and urban infrastructure.

Indexed as

Cardiovascular DiseasesRainRespiratory Tract DiseasesCause of DeathGlobal HealthHumansMortalityTime Factors

Identifiers

PMID39384295
PMCPMC12036573

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.