Evidence map›Paper›PMID 39384216›Full record

ArticleThe clinical respiratory journal2024

Solitary Renal Metastases From Stage IA Primary Lung Adenocarcinoma With Co-Alteration of EGFR, RB1, and MAP3K1: A Case Report.

Zhu Qin, Chen Xin, He Zhenzhen, Xie Liang, Yi Wei, Li Shuben

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in The clinical respiratory journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhu QinDepartment of Radiation Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.ORCID https://orcid.org/0009-0004-2557-4761
Chen XinDepartment of Radiation Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
He ZhenzhenDepartment of Pathology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Xie LiangDepartment of Radiation Oncology, Guangxi Academy of Medical Sciences & the People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Yi WeiDepartment of Radiation Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Li ShubenDepartment of Thoracic Surgery, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.ORCID https://orcid.org/0000-0002-6012-7500

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of 59-year-old female with solitary bilateral renal metastases after surgery of stage IA primary lung adenocarcinoma who underwent next-generation sequencing (NGS) of both lesions. The patient received right upper lobectomy and lymph node dissection, which revealed primary invasive lung adenocarcinoma (pT1cN0M0, stage IA3). Two years following this, positron emission tomography-computed tomography (PET/CT) revealed multiple masses in both kidneys without other distant metastases, and ultrasonography-guided puncture biopsy indicated the presence of metastatic lung adenocarcinoma. The NGS of both the primary and metastatic lesions revealed the co-alteration of epidermal growth factor receptor (EGFR), RB transcriptional corepressor 1 (RB1), and mitogen-activated protein kinase kinase 1 (MAP3K1), which is potentially associated with the risk of renal metastasis in early postoperative non-small cell lung cancer.

Indexed as

Adenocarcinoma of LungErbB ReceptorsKidney NeoplasmsLung NeoplasmsFemaleHigh-Throughput Nucleotide SequencingHumansMAP Kinase Kinase Kinase 1Middle AgedNeoplasm StagingPneumonectomyPositron Emission Tomography Computed TomographyRetinoblastoma Binding ProteinsUbiquitin-Protein LigasesEGFR protein, humanErbB ReceptorsMAP Kinase Kinase Kinase 1RB1 protein, humanRetinoblastoma Binding ProteinsUbiquitin-Protein LigasesEGFR, RB1, and MAP3K1 co‐alterationlung adenocarcinomarenal metastasis

Identifiers

PMID39384216
PMCPMC11464089

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.