Evidence map›Paper›PMID 39383842›Full record

ArticleImmunity2024

Superficial ice and deep blaze: A defense strategy of the skin.

Zhuoqiong Qiu, Wei Li

Abstract readComment
PubMed Publisher
In one paragraph

Article in Immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Zhuoqiong QiuDepartment of Dermatology, Shanghai Institute of Dermatology, Huashan Hospital, Fudan University, Shanghai, China; Department of Dermatology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Wei LiDepartment of Dermatology, Shanghai Institute of Dermatology, Huashan Hospital, Fudan University, Shanghai, China. Electronic address: liweiderma@fudan.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It's crucial for skin to establish efficient defense strategies. Liu et al. reveal that the transcription factor ZNF750 recruits the histone demethylase KDM1A to silence pattern recognition receptors in the outer epidermis, making their expression limited to deeper, undifferentiated keratinocytes to address threats penetrating the skin.

Indexed as

KeratinocytesSkinTranscription FactorsAnimalsDNA-Binding ProteinsEpidermisHistone DemethylasesHumansReceptors, Pattern RecognitionDNA-Binding ProteinsHistone DemethylasesKDM1A protein, humanReceptors, Pattern RecognitionTranscription Factors

Identifiers

PMID39383842

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.