Evidence map›Paper›PMID 39383839›Full record

ArticleImmunity2024

Oligodendrocytes go with the flow: Meningeal lymphatics promote myelin integrity.

Eric D Garcia, Jonah R Chan

Abstract readComment
PubMed Publisher
In one paragraph

Article in Immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Eric D GarciaDepartment of Neurology, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA; Neuroscience Graduate Program, University of California San Francisco, San Francisco, CA, USA. Electronic address: eric.garcia@ucsf.edu.
Jonah R ChanDepartment of Neurology, Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA, USA; Neuroscience Graduate Program, University of California San Francisco, San Francisco, CA, USA. Electronic address: jonah.chan@ucsf.edu.

Funding

Cell-type, circuit and network mechanisms of adult oligodendrogenesis in memory storage and retrievalR01MH125515 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHAN, JONAH R, KHEIRBEK, MAZEN A · 2021 to 2025
$3.4M
Neuropeptides as axonal determinants for oligodendrocyte differentiation and myelinationR01NS115746 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHAN, JONAH R · 2021 to 2025
$1.9M
NIMH NIH HHS R01 MH125515NINDS NIH HHS R01 NS115746
6 · The paper itself

Abstract

The meningeal lymphatics system plays diverse roles in facilitating neuroimmune function at brain borders, yet its specific contribution toward glial function and homeostasis is not known. In this issue of Immunity, Das Neves et al. (2024) describe a novel role for the meningeal lymphatics in maintaining oligodendrocyte survival and myelination.

Indexed as

MeningesMyelin SheathOligodendrogliaAnimalsHomeostasisHumansLymphatic Vessels

Identifiers

PMID39383839

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.