Evidence map›Paper›PMID 39383239›Full record

ArticleScience advances2024

Ultrathin crystalline silicon-based omnidirectional strain gauges for implantable/wearable characterization of soft tissue biomechanics.

Bofan Hu, Dian Xu, Yuting Shao, Zhongyi Nie, Pengchuan Liu, Jinbao Li, Lianjie Zhou, Pei Wang, Ningge Huang, Junhan Liu and 7 more

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Autonomous Polymer Frameworks for Sustainable Tissue-Interfaced Plastic Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Bofan HuShanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Institute of Optoelectronics, Department of Materials Science, Fudan University, Shanghai, China.ORCID 0009-0004-0897-7032
Dian XuSchool of Mechanics and Aerospace Engineering, State Key Laboratory of Structural Analysis, Optimization and CAE Software for Industrial Equipment, and International Research Center for Computational Mechanics, Dalian University of Technology, Dalian 116024, China.ORCID 0000-0001-9373-924X
Yuting ShaoShanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Institute of Optoelectronics, Department of Materials Science, Fudan University, Shanghai, China.ORCID 0000-0002-2654-7288
Zhongyi NieDepartment of Biomedical Engineering, College of Future technology, Peking University, Beijing 100871, China.ORCID 0009-0008-0869-9588
Pengchuan LiuShanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Institute of Optoelectronics, Department of Materials Science, Fudan University, Shanghai, China.
Jinbao LiSchool of Mechanics and Aerospace Engineering, State Key Laboratory of Structural Analysis, Optimization and CAE Software for Industrial Equipment, and International Research Center for Computational Mechanics, Dalian University of Technology, Dalian 116024, China.ORCID 0009-0000-7031-4636
Lianjie ZhouShanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Institute of Optoelectronics, Department of Materials Science, Fudan University, Shanghai, China.ORCID 0000-0002-9285-2176
Pei WangDepartment of Cardiothoracic Surgery, The Second Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200003, China.ORCID 0000-0002-8356-3954
Ningge HuangShanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Institute of Optoelectronics, Department of Materials Science, Fudan University, Shanghai, China.
Junhan LiuShanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Institute of Optoelectronics, Department of Materials Science, Fudan University, Shanghai, China.
Yifei LuShanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Institute of Optoelectronics, Department of Materials Science, Fudan University, Shanghai, China.
Zhongyuan WuShanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Institute of Optoelectronics, Department of Materials Science, Fudan University, Shanghai, China.
Bo WangSchool of Mechanics and Aerospace Engineering, State Key Laboratory of Structural Analysis, Optimization and CAE Software for Industrial Equipment, and International Research Center for Computational Mechanics, Dalian University of Technology, Dalian 116024, China.
Yongfeng MeiShanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Institute of Optoelectronics, Department of Materials Science, Fudan University, Shanghai, China.ORCID 0000-0002-3314-6108
Mengdi HanDepartment of Biomedical Engineering, College of Future technology, Peking University, Beijing 100871, China.ORCID 0000-0002-7552-7398
Rui LiSchool of Mechanics and Aerospace Engineering, State Key Laboratory of Structural Analysis, Optimization and CAE Software for Industrial Equipment, and International Research Center for Computational Mechanics, Dalian University of Technology, Dalian 116024, China.ORCID 0000-0001-6051-4204
Enming SongShanghai Frontiers Science Research Base of Intelligent Optoelectronics and Perception, Institute of Optoelectronics, Department of Materials Science, Fudan University, Shanghai, China.ORCID 0000-0002-2658-904X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monitoring soft-tissue biomechanics is of interest in biomedical research and clinical treatment of diseases. An important focus is biointegrated strain gauges that track time-dependent mechanics of targeted tissues with deforming surfaces over multidirections. Existing methods provide limited gauge factors, tailored for sensing within specific directions under quasi-static conditions. We present development and applicability of implantable/wearable strain gauges that integrate multiple ultrathin monocrystalline silicon-based sensors aligned with different directions, in stretchable formats for dynamically monitoring direction angle-sensitive strain. We experimentally and computationally establish operational principles, with theoretical systems that enable determination of intensities and direction of applied strains at an omnidirectional scale. Wearable evaluations range from cardiac pulse to intraocular pressure monitoring of eyeballs. The device can evaluate cardiac disorders of myocardial infarction and hypoxia of living rats and locate the pathological orientation associated with infarction, in designs with possibilities as biodegradable implants for stable operation. These findings create clinical significance of the devices for monitoring complex dynamic biomechanics.

Indexed as

SiliconWearable Electronic DevicesAnimalsBiomechanical PhenomenaHumansMyocardial InfarctionProstheses and ImplantsRatsStress, MechanicalSilicon

Identifiers

PMID39383239
PMCPMC11463283

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.