Evidence map›Paper›PMID 39382984›Full record

ArticleJournal of the American Society of Nephrology : JASN2025

Targeting Krüppel-Like Factor 2 as a Novel Therapy for Glomerular Endothelial Cell Injury in Diabetic Kidney Disease.

Lulin Min, Yixin Chen, Ruijie Liu, Zhengzhe Li, Leyi Gu, Sandeep Mallipattu, Bhaskar Das, Kyung Lee, John Cijiang He, Fang Zhong

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. IGFBP6 contributes to vascular resilience.Nature cardiovascular research · 2025
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lulin MinDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
Yixin ChenDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
Ruijie LiuDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
Zhengzhe LiDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
Leyi GuDepartment of Nephrology, School of Medicine, Renji Hospital, Shanghai Jiao Tong University, Shanghai, China.ORCID 0000-0003-4358-0132
Sandeep MallipattuDivision of Nephrology, Department of Medicine, Stony Brook University, Stony Brook, New York.ORCID 0000-0002-6324-7807
Bhaskar DasDepartment of Pharmaceutical Sciences, State University of New York at Buffalo, Buffalo, New York.ORCID 0000-0002-5837-027
Kyung LeeDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.ORCID 0000-0002-9756-1765
John Cijiang HeDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.ORCID 0000-0002-1502-2849
Fang ZhongDivision of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.ORCID 0000-0002-3165-6884

Funding

The role of Vpr-mediated cell cycle dysregulation in HIV-associated kidney diseaseR01DK133912 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI John Cijiang He, Mary E. Klotman · 2022 to 2026
$3.7M
Transcriptional control of mitochondrial function by KLF6 in diabetic kidney diseaseR01DK112984 · NIDDK · STATE UNIVERSITY NEW YORK STONY BROOK · PI Sandeep K Mallipattu · 2017 to 2026
$3.5M
Role of RTN1A in the Progression of Diabetic NephropathyR01DK109683 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HE, JOHN CIJIANG · 2016 to 2023
$3.3M
PP2A as a drug target for diabetic kidney diseaseR01DK122980 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HE, JOHN CIJIANG, LIU, RUIJIE · 2020 to 2024
$2.9M
Mechanisms mediating podocyte-parietal epithelial cell crosstalk in proliferative glomerulopathiesR01DK121846 · NIDDK · STATE UNIVERSITY NEW YORK STONY BROOK · PI HE, JOHN CIJIANG, MALLIPATTU, SANDEEP K · 2020 to 2024
$2.7M
The Role of LRG1 in Diabetic Kidney DiseaseR01DK117913 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Bhaskar Chandra Das, Kyung Lee · 2018 to 2026
$2.6M
KLF2 is a novel endoprotective target for DKDR01DK141510 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Bhaskar Chandra Das, John Cijiang He · 2024 to 2026
$2.2M
Role of RARRES1 in diabetic kidney diseaseR01DK129467 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HE, JOHN CIJIANG, LEE, KYUNG · 2021 to 2024
$1.8M
BLRD VA I01 BX000345BLRD VA I01 BX003698NIDDK NIH HHS R01 DK109683NIDDK NIH HHS R01DK109683, R01DK122980, and R01DK129467NIDDK NIH HHS R01 DK112984NIDDK NIH HHS R01 DK117913NIDDK NIH HHS R01DK117913, R01DK129467, 1R01DK133912NIDDK NIH HHS R01 DK121846NIDDK NIH HHS R01 DK122980NIDDK NIH HHS R01 DK129467NIDDK NIH HHS R01 DK133912NIDDK NIH HHS R01 DK141510VA Merit Award I01BX000345
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39382984
PMCPMC11801754

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.