Evidence map›Paper›PMID 39382786›Full record

ReviewMikrochimica acta2024

Recent advances in surface plasmon resonance for the detection of ovarian cancer biomarkers: a thorough review.

Shahnam Valizadeh Shahbazlou, Somayeh Vandghanooni, Bahareh Dabirmanesh, Morteza Eskandani, Sadegh Hasannia

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mikrochimica acta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shahnam Valizadeh ShahbazlouDepartment of Biochemistry, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Somayeh VandghanooniHematology and Oncology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Bahareh DabirmaneshDepartment of Biochemistry, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Morteza EskandaniResearch Center for Pharmaceutical Nanotechnology (RCPN), Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran. eskandanim@tbzmed.ac.ir.ORCID http://orcid.org/0000-0003-2282-4871
Sadegh HasanniaDepartment of Biochemistry, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran. hasannia@modares.ac.ir.

Funding

Research Center for Pharmaceutical Nanotechnology 66682
6 · The paper itself

Abstract

Early detection of ovarian cancer (OC) is crucial for effective management and treatment, as well as reducing mortality rates. However, the current diagnostic methods for OC are time-consuming and have low accuracy. Surface plasmon resonance (SPR) biosensors offer a promising alternative to conventional techniques, as they enable rapid and less invasive screening of various circulating indicators. These biosensors are widely used for biomolecular interaction analysis and detecting tumor markers, and they are currently being investigated as a rapid diagnostic tool for early-stage cancer detection. Our main focus is on the fundamental concepts and performance characteristics of SPR biosensors. We also discuss the latest advancements in SPR biosensors that enhance their sensitivity and enable high-throughput quantification of OC biomarkers, including CA125, HE4, CEA, and CA19-9. Finally, we address the future challenges that need to be overcome to advance SPR biosensors from research to clinical applications. The ultimate goal is to facilitate the translation of SPR biosensors into routine clinical practice for the early detection and management of OC.

Indexed as

Biomarkers, TumorOvarian NeoplasmsSurface Plasmon ResonanceBiosensing TechniquesCA-125 AntigenFemaleHumansBiomarkers, TumorCA-125 AntigenNanotechnologyOvarian cancerSensorSPRSPRiSurface plasmon resonance

Identifiers

PMID39382786

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.