Evidence map›Paper›PMID 39382739›Full record

ArticleProbiotics and antimicrobial proteins2025

The Effect of Lacticaseibacillus rhamnosus, Lacticaseibacillus paracasei, and Bifidobacterium animalis ssp. lactis on the Prevention of Asthma in an Animal Model.

Líris Marini Dias Coelho, Vanessa Maciel Braulio da Fonseca, Ivana Golçalves Labadessa, Sergio Luiz Salvador, Marina Del Arco Mastrange, Ana Flávia Gembre, Núbia Sabrina Martins, Vânia Luiza Deperon Bonato, Élcio Oliveira Vianna, Marcos Carvalho Borges

Abstract read
PubMed Publisher
In one paragraph

Article in Probiotics and antimicrobial proteins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Líris Marini Dias CoelhoDepartament of Internal Medicine, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, 14048-900, Brazil.
Vanessa Maciel Braulio da FonsecaDepartament of Internal Medicine, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, 14048-900, Brazil.
Ivana Golçalves LabadessaDepartament of Internal Medicine, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, 14048-900, Brazil.
Sergio Luiz SalvadorDepartment of Clinical Analyses, School of Pharmaceutical Sciences of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, SP, 14040-903, Brazil.
Marina Del Arco MastrangeDepartment of Clinical Analyses, School of Pharmaceutical Sciences of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, SP, 14040-903, Brazil.
Ana Flávia GembreDepartment of Biochemistry and Immunology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil.
Núbia Sabrina MartinsDepartment of Biochemistry and Immunology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil.
Vânia Luiza Deperon BonatoDepartment of Biochemistry and Immunology, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, Brazil.
Élcio Oliveira ViannaDepartament of Internal Medicine, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, 14048-900, Brazil.
Marcos Carvalho BorgesDepartament of Internal Medicine, Ribeirao Preto Medical School, University of Sao Paulo, Ribeirao Preto, 14048-900, Brazil. marcosborges@fmrp.usp.br.

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.510924/2020-00Fundação de Amparo à Pesquisa do Estado de São Paulo 2017/21035-8
6 · The paper itself

Abstract

The increase in the prevalence of asthma, particularly in urban communities, has encouraged investigations into preventive strategies. The hygiene theory proposes that early exposure to infections and unhygienic conditions during childhood influences immune system development, potentially protecting against allergic diseases. The mechanisms involved are related to alterations in the intestinal microbiota, such as with probiotics. This study aimed to evaluate the preventive effect of Lacticaseibacillus rhamnosus, Lacticaseibacillus paracasei, and Bifidobacterium animalis ssp. lactis, administered isolated or in combination, at various concentrations, on asthma in an animal model. Mice received two concentrations (1 × 10

Indexed as

AsthmaBifidobacterium animalisLacticaseibacillus paracaseiLacticaseibacillus rhamnosusProbioticsAnimalsDisease Models, AnimalFemaleMiceMice, Inbred BALB CAnimal modelAsthmaOvalbuminPreventionProbiotics

Identifiers

PMID39382739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.