Evidence map›Paper›PMID 39382121›Full record

ArticleBJS open2024

Surgical complications after immediate implant-based breast reconstruction for breast cancer in women over 65 years.

Yihang Liu, Anna L V Johansson, Ira Oikonomou, Axel Frisell, Hannah C Adam, Dhirar Ansarei, Martin Halle, Helena Sackey, Jana de Boniface

Abstract read
In one paragraph

Article in BJS open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yihang LiuDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Anna L V JohanssonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Ira OikonomouDepartment of Surgery, South General Hospital, Stockholm, Sweden.
Axel FrisellDepartment of Dermatology and Venerology, Karolinska University Hospital, Stockholm, Sweden.ORCID 0000-0002-2600-3483
Hannah C AdamDepartment of Orthopaedic Surgery, Danderyd Hospital, Stockholm, Sweden.ORCID 0000-0002-1153-8477
Dhirar AnsareiDepartment of Surgery, Västmanlands sjukhus Västerås, Västerås, Stockholm, Sweden.
Martin HalleDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Helena SackeyDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Jana de BonifaceDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0001-9518-0902

Funding

Stockholm County Council
6 · The paper itself

Abstract

backgroundWhile immediate breast reconstruction rates in breast cancer are increasing, they remain low in women over 65 years old. The aim was to investigate surgical outcomes in women older than 65 years receiving implant-based immediate breast reconstruction.

methodThe population-based Stockholm Breast Reconstruction Database includes all adult women with breast cancer receiving an implant-based immediate breast reconstruction in Stockholm, Sweden, 2005-2015. Primary outcomes within 30 days from immediate breast reconstruction were: infection requiring antibiotics and reoperation on. Implant removal was a secondary outcome. Women more than 65 years were compared with younger age groups. Chi-square tests and multivariable logistic regression were applied for the primary outcomes, and Kaplan-Meier analysis for the secondary outcome.

resultsAmong 1749 cases of immediate breast reconstruction, 140 (8.0%) were in women more than 65 years. Median follow-up was 74 months (1-198). Postoperative infection was not more common in women older than 65 years old (22 of 140, 15.7%) than in women under 65 years old (303 of 1609, 18.8%; P = 0.221). Reoperation on was more frequent in women older than 65 years than in other age groups (more than 65: 8.6%; 50-64: 6.5%; 40-49: 3.5%; less than 40: 1.6%; P < 0.001), however, age older than 65 years was not an independent risk factor in the multivariable analysis (OR 1.00, 95% c.i. 0.44 to 2.28). Overall, 6-year probability of implant removal was 11.4%, (8.1% due to complications and 3.3% due to patient preference). There was no statistically significant difference between age groups for either reason (P = 0.085 and P = 0.794 respectively).

conclusionOlder age alone was not associated with worse surgical outcomes after implant-based immediate breast reconstruction in highly selected patients older than 65 years when compared with their younger counterparts.

Indexed as

Breast ImplantsBreast NeoplasmsReoperationAdultAgedAge FactorsBreast ImplantationDevice RemovalFemaleHumansKaplan-Meier EstimateLogistic ModelsMammaplastyMastectomyMiddle AgedPostoperative Complications

Identifiers

PMID39382121
PMCPMC11462148

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.