Evidence map›Paper›PMID 39382020›Full record

ReviewNanomedicine (London, England)2024

Enhancing radiotherapy for melanoma: the promise of high-Z metal nanoparticles in radiosensitization.

Abolfazl Bemidinezhad, Shaghayegh Radmehr, Negin Moosaei, Zohreh Efati, Prashant Kesharwani, Amirhossein Sahebkar

Abstract readReview
In one paragraph

Review in Nanomedicine (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Abolfazl BemidinezhadPharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad, Iran.
Shaghayegh RadmehrCheeloo College of Medicine, Shandong University, Jinan, China.
Negin MoosaeiMaterials Science & Engineering Faculty, K. N. Toosi University of Technology, Tehran, Iran.
Zohreh EfatiStudent Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.
Prashant KesharwaniDepartment of Pharmaceutics, School of Pharmaceutical Education & Research, Jamia Hamdard, New Delhi 110062, India.ORCID 0000-0002-0890-769X
Amirhossein SahebkarCenter for Global health Research, Saveetha Medical College & Hospitals, Saveetha Institute of Medical & Technical Sciences, Saveetha University, India.ORCID 0000-0002-8656-1444

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanoma is a type of skin cancer that can be challenging to treat, especially in advanced stages. Radiotherapy is one of the main treatment modalities for melanoma, but its efficacy can be limited due to the radioresistance of melanoma cells. Recently, there has been growing interest in using high-Z metal nanoparticles (NPs) to enhance the effectiveness of radiotherapy for melanoma. This review provides an overview of the current state of radiotherapy for melanoma and discusses the physical and biological mechanisms of radiosensitization through high-Z metal NPs. Additionally, it summarizes the latest research on using high-Z metal NPs to sensitize melanoma cells to radiation, both

Indexed as

MelanomaMetal NanoparticlesRadiation-Sensitizing AgentsAnimalsHumansSkin NeoplasmsRadiation-Sensitizing Agentsgold nanoparticlehigh-Z materialmelanomaradiosensitizationradiotherapy

Identifiers

PMID39382020
PMCPMC11492696

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.