ArticleFrontiers in public health2024
Air pollutants and primary liver cancer mortality: a cohort study in crop-burning activities and forest fires area.
Article in Frontiers in public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Screening air pollutants-related genes to construct a prognostic risk model for lung adenocarcinoma and analyzing its immune microenvironment.Journal of thoracic disease · 2026Article
- Time-varying exposure to ambient air pollution and mortality among colon cancer patients in northern Thailand: a 15-year retrospective cohort study.Frontiers in public health · 2026Article
- Impact of PM2.5 exposure on acute toxicities and survival outcomes in radiotherapy for cervical cancer.Scientific reports · 2025Article
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11 authors.
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Abstract
Introduction: Northern Thailand experiences high levels of air pollution in the dry season due to agricultural waste burning and forest fires. Some air pollutants can enter the bloodstream, and the liver has the role of detoxifying these along with other harmful substances. In this study, we assessed the effects of long-term exposure to air pollutants on liver cancer mortality in this area. Methods: A cohort of 10,859 primary liver cancer patients diagnosed between 2003 and 2018 and followed up to the end of 2020 were included in the study. Extended time-varying covariates of the annually averaged pollutant concentrations updated each year were utilized. The associations between air pollutants and mortality risk were examined by using a Cox proportional hazard model. Results: Metastatic cancer stage had the highest adjusted hazard ratio (aHR) of 3.57 (95% confidence interval (CI):3.23-3.95). Being male (aHR = 1.10; 95% CI: 1.04-1.15), over 60 years old (aHR = 1.16; 95% CI: 1.11-1.21), having a history of smoking (aHR = 1.16; 95%CI: 1.11-1.22), and being exposed to a time-updated local concentration of PM Conclusion: We found that air pollution is one of several detrimental factors on the mortality risk of liver cancer.
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