Evidence map›Paper›PMID 39381685›Full record

ArticleJournal of the Endocrine Society2024

Bone Marrow Adiposity Alterations in Postmenopausal Women With Type 2 Diabetes Are Site-Specific.

Sammy Badr, Anne Cotten, Daniela Lombardo, Stefan Ruschke, Dimitrios C Karampinos, Nassima Ramdane, Michael Genin, Julien Paccou

Abstract read
In one paragraph

Article in Journal of the Endocrine Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sammy BadrDepartment of Radiology and Musculoskeletal Imaging, University Lille, CHU Lille, MABlab ULR 4490, F-59000 Lille, France.
Anne CottenDepartment of Radiology and Musculoskeletal Imaging, University Lille, CHU Lille, MABlab ULR 4490, F-59000 Lille, France.
Daniela LombardoDepartment of Rheumatology, CHU Lille, F-59000 Lille, France.
Stefan RuschkeDepartment of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, 81675 Munich, Germany.
Dimitrios C KarampinosDepartment of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, School of Medicine and Health, Technical University of Munich, 81675 Munich, Germany.
Nassima RamdaneDepartment of Biostatistics, CHU Lille, F-59000 Lille, France.
Michael GeninULR 2694-METRICS: Évaluation des Technologies de Santé et des Pratiques Médicales, University Lille, CHU Lille, F-59000 Lille, France.
Julien PaccouDepartment of Rheumatology, University Lille, CHU Lille, MABlab ULR 4490, F-59000 Lille, France.ORCID https://orcid.org/0000-0001-6599-8623

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Context: Bone marrow adiposity (BMAT) alterations in patients with type 2 diabetes mellitus (T2DM) may contribute to adverse bone effects. Objective: Characterization of BMAT content and composition in patients with well-controlled T2DM. Methods: This cross-sectional study included 2 groups of postmenopausal women: one with T2DM and the other without. The proton density fat fraction (PDFF) of the lumbar spine and proximal femur, comprising the femoral head, neck, and diaphysis, was assessed using chemical shift-based water-fat separation imaging (WFI). Magnetic resonance imaging with spectroscopy ( Results: Among 199 participants, patients with T2DM (n = 29) were significantly heavier ( Conclusion: The content and composition of BMAT are modified in postmenopausal women with T2DM and these changes occur at specific sites.

Indexed as

bone marrow adipose tissuebone mineral densitydiabetes mellitusglycated hemoglobinosteoporosis

Identifiers

PMID39381685
PMCPMC11458911

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.