Evidence map›Paper›PMID 39381445›Full record

ArticleCureus2024

Navigating Diagnosis and Treatment Dilemmas in Visceral Leishmaniasis Reactivation in a HIV-Positive Patient.

Dinusha Gayathri, Buddhika Dhananjalee Alahakoon, Udaya Ralapanawa, Ganga Pathirana, Godayalage Chamari Madushani Weerasooriya

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dinusha GayathriGeneral Medicine, Postgraduate Institute of Medicine, Colombo, LKA.
Buddhika Dhananjalee AlahakoonGeneral Medicine, Teaching Hospital Peradeniya, Peradeniya, LKA.
Udaya RalapanawaFaculty of Medicine, University of Peradeniya, Peradeniya, LKA.
Ganga PathiranaVenereologist, Teaching Hospital Kandy, Kandy, LKA.
Godayalage Chamari Madushani WeerasooriyaHematology, Postgraduate Institute of Medicine, Colombo, LKA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reactivation of visceral leishmaniasis (VL) in human immunodeficiency virus (HIV)-positive patients poses complex management challenges, requiring tailored treatment approaches and robust follow-up strategies. There are very few case reports of visceral leishmaniasis (VL) published in Sri Lanka as of today. Here, we present a case of a 38-year-old, HIV-positive male who was treated for a reactivation of VL. He presented with a prolonged febrile illness without an identifiable infection focus. The evaluation confirmed VL reactivation. Using current evidence-based guidelines, our patient was treated with intravenous liposomal amphotericin B and achieved a parasitological cure.  By exploring the challenges associated with managing VL among HIV-positive individuals, we emphasize the importance of reliable follow-up protocols and investigations to assess treatment success, ensuring optimal patient outcomes.

Indexed as

dilemmashiv positivereactivationtreatmentvisceral leishmaniasis

Identifiers

PMID39381445
PMCPMC11458552

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.