Evidence map›Paper›PMID 39381386›Full record

ReviewJournal of hand surgery global online2024

Development of Biomaterials for Addressing Upper Extremity Peripheral Nerve Gaps.

Bassam M Smadi, Ramin Shekouhi, Armina Azizi, Harvey Chim

Abstract readReview
In one paragraph

Review in Journal of hand surgery global online, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bassam M SmadiJ Crayton Pruitt Department of Biomedical Engineering, University of Florida, Gainesville, FL.
Ramin ShekouhiDivision of Plastic & Reconstructive Surgery, Department of Surgery, University of Florida College of Medicine, Gainesville, FL.
Armina AziziDivision of Plastic & Reconstructive Surgery, Department of Surgery, University of Florida College of Medicine, Gainesville, FL.
Harvey ChimDivision of Plastic & Reconstructive Surgery, Department of Surgery, University of Florida College of Medicine, Gainesville, FL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral nerve injuries within the upper extremities can lead to impaired function and reduced quality of life. Although autografts have traditionally served as the primary therapeutic approach to bridge nerve gaps, these present challenges related to donor site morbidity. This review delves into the realm of biomaterials tailored for addressing nerve gaps. Biomaterials, whether natural or synthetically derived, offer the potential not only to act as scaffolds for nerve regeneration but also to be enhanced with growth factors and agents that promote nerve recovery. The historical progression of these biomaterials as well as their current applications, advantages, inherent challenges, and future impact in the arena of regenerative medicine are discussed. By providing a comprehensive overview, we aim to shed light on the transformative potential of biomaterials in peripheral nerve repair and the path toward refining their efficacy in clinical settings.

Indexed as

Biomaterials developmentNerve regenerationPeripheral nerveTissue engineeringUpper extremities

Identifiers

PMID39381386
PMCPMC11456663

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.