ArticleFrontiers in nutrition2024
Reduction in Lp(a) after a medically supervised, prolonged water-only fast followed by a whole-plant-food diet free of added salt, oil, and sugar: a case report.
Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Dietary Quality Along a Plant-Based Continuum: The Role of Added Salt, Oil, and Sugar in Chronic Disease Risk.Nutrients · 2026Review
- Article
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Authors and funding
4 authors.
Funding
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Abstract
Lipoprotein(a) [Lp(a)] is a low-density lipoprotein (LDL) associated with increased cardiovascular disease (CVD) risk. High Lp(a) levels are genetically determined and lack effective pharmacotherapy. This case report describes a 67-year-old, vegan male with elevated blood pressure (BP), total cholesterol (TC), LDL, and Lp(a) who underwent a 10-day, medically supervised water-only fast followed by a 6-week SOS-free diet (free of added salt, oil, and sugar). At the 6-week-follow-up visit, he experienced significant reductions in several CVD risk markers, including blood pressure, total cholesterol, LDL, and high-sensitivity C-reactive protein. He also experienced an unexpected decrease in Lp(a), from 236.3 nmol/L to 143.4 nmol/L (39%). This decrease is comparable to reductions achieved with proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors. These findings suggest that prolonged water-only fasting and/or an SOS-free diet may be an effective alternative approach for managing high Lp(a) levels and reducing CVD risk in a vegan population, warranting further research.
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