Evidence map›Paper›PMID 39381329›Full record

ArticleFrontiers in physiology2024

Taravana syndrome and posterior reversible encephalopathy syndrome: a microbubble hypothesis for neurological accidents in breath-hold divers.

Arnaud Druelle, Olivier Castagna, Romain Roffi, Pierre Louge, Anthony Faivre, Jean-Eric Blatteau

Abstract read
In one paragraph

Article in Frontiers in physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Advances in breath-hold diving research: a state-of-the-art review.European journal of applied physiology · 2026
    Review
  3. Review
  4. Article
  5. Inert Gas Mild Pressure Action on Healthy Humans: The "IPA" Study.International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arnaud Druelle *Service de Médecine Hyperbare et d'Expertise Plongée (SMHEP), Hôpital d'Instruction des Armées Sainte-Anne, Toulon, France.
Olivier CastagnaEquipe de Recherche Subaquatique et Hyperbare, Institut de Recherche Biomédicale des Armées, Toulon, France.
Romain RoffiService de Médecine Hyperbare et d'Expertise Plongée (SMHEP), Hôpital d'Instruction des Armées Sainte-Anne, Toulon, France.
Pierre LougeService de Médecine Hyperbare et d'Expertise Plongée (SMHEP), Hôpital d'Instruction des Armées Sainte-Anne, Toulon, France.
Anthony FaivreUnité Neurovasculaire, Hôpital d'Instruction des Armées Sainte-Anne, Toulon, France.
Jean-Eric Blatteau *Service de Médecine Hyperbare et d'Expertise Plongée (SMHEP), Hôpital d'Instruction des Armées Sainte-Anne, Toulon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breath-hold diving is a challenging activity that can lead to serious and dangerous complications, such as the "Taravana" syndrome. This syndrome is characterized by the onset of neurological symptoms after deep or repeated dives. The main clinical manifestations are cerebral, including stroke and cognitive impairment. The pathophysiology of Taravana syndrome is still widely debated, but the most accepted theory is that it is a specific form of decompression sickness. We have reviewed the main theories explaining the onset of Taravana syndrome and, through the description of a particularly illustrative case of a freediver using an underwater scooter, we have formulated a hypothesis according to which micro-bubbles formed directly in cerebral structures would be at the origin of this syndrome. MRI showed diffuse encephalopathy with vasogenic edema. Analysis of the radiological sequences did not suggest an ischemic or embolic mechanism. This finding is likely to be associated with the diagnosis of posterior reversible encephalopathy syndrome. The rapid ascent speeds associated with underwater scooter use could potentially result in the formation of nitrogen micro-bubbles in the capillaries of brain tissue. The emergence of scooters in freediving can be a hazard because of their ability to facilitate very rapid ascents. It is therefore essential to take preventive measures to ensure the safety of users of these devices.

Indexed as

breath-hold divingbubbledecompression sicknessMRIneurological symptomsposterior reversible encephalopathy syndromeTaravanaunderwater scooter

Identifiers

PMID39381329
PMCPMC11458415

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.