Evidence map›Paper›PMID 39380440›Full record

ArticleACS nano2024

Patient-Specific Nanoparticle Targeting in Human Leukemia Blood.

Yi Ju, Shiyao Li, Abigail Er Qi Tan, Emily H Pilkington, Paul T Brannon, Magdalena Plebanski, Jiwei Cui, Frank Caruso, Kristofer J Thurecht, Constantine Tam and 1 more

Abstract read
In one paragraph

Article in ACS nano, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. cDC1 Subtype-Specific In Vivo Targeting of Liposomes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yi JuSchool of Science, RMIT University, Melbourne, Victoria 3000, Australia.ORCID 0000-0003-0103-1207
Shiyao LiSchool of Science, RMIT University, Melbourne, Victoria 3000, Australia.ORCID 0000-0002-8053-7005
Abigail Er Qi TanDepartment of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria 3000, Australia.
Emily H PilkingtonDepartment of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria 3000, Australia.
Paul T BrannonMaterials Characterisation and Fabrication Platform, The University of Melbourne, Parkville, Victoria 3010, Australia.
Magdalena PlebanskiSchool of Health and Biomedical Sciences, RMIT University, Bundoora, Victoria 3083, Australia.
Jiwei CuiKey Laboratory of Colloid and Interface Chemistry of the Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong 250100, China.ORCID 0000-0003-1018-4336
Frank CarusoDepartment of Chemical Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia.ORCID 0000-0002-0197-497X
Kristofer J ThurechtAustralian Institute for Bioengineering and Nanotechnology, University of Queensland, St Lucia 4072, Australia.ORCID 0000-0002-4100-3131
Constantine TamDepartment of Clinical Haematology, The Royal Melbourne Hospital and Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia.
Stephen J KentDepartment of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria 3000, Australia.ORCID 0000-0002-8539-4891

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibody-directed targeting of chemotherapeutic nanoparticles to primary human cancers holds promise for improving efficacy and reducing off-target toxicity. However, clinical responses to targeted nanomedicines are highly variable. Herein, we prepared and examined a matrix of 9 particles (organic and inorganic particles of three surface chemistries with and without antibody functionalization) and developed an

Indexed as

DoxorubicinLeukemia, Lymphocytic, Chronic, B-CellNanoparticlesPolyethylene GlycolsAgedDrug Delivery SystemsFemaleHumansLiposomesMalePhagocytosisDoxorubicinLiposomesPolyethylene Glycolsbiomolecular coronashuman blood modelimmunoglobulinsoff-targeting cytotoxicityparticle−immune cell interactionsprecision medicine

Identifiers

PMID39380440
PMCPMC11503784

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.