Evidence map›Paper›PMID 39380420›Full record

ArticleJournal of fish diseases2025

The Impact of Exposure Dosage and Host Genetics on the Shedding Kinetics of Flavobacterium psychrophilum in Rainbow Trout.

Darbi R Jones, Jeremy Everson, Timothy D Leeds, Gregory D Wiens, Andrew R Wargo

Abstract read
In one paragraph

Article in Journal of fish diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Darbi R JonesVirginia Institute of Marine Science, William & Mary, Gloucester Point, Virginia, USA.
Jeremy EversonNational Center for Cool and Cold Water Aquaculture, Kearneysville, West Virginia, USA.
Timothy D LeedsNational Center for Cool and Cold Water Aquaculture, Kearneysville, West Virginia, USA.
Gregory D WiensNational Center for Cool and Cold Water Aquaculture, Kearneysville, West Virginia, USA.ORCID https://orcid.org/0000-0002-5478-7780
Andrew R WargoVirginia Institute of Marine Science, William & Mary, Gloucester Point, Virginia, USA.ORCID https://orcid.org/0000-0002-9209-3077

Funding

The Impacts of Host Vaccination and Genetic Resistance on Pathogen TransmissionR01GM113233 · NIGMS · VIRGINIA INSTITUTE OF MARINE SCIENCE · PI WARGO, ANDREW R · 2014 to 2017
$2.0M
NIGMS NIH EEID R01GM113233NIGMS NIH HHS R01 GM113233USDA Agricultural Research Service CRIS Project 8082-32000-007Virginia Institute of Marine Science
6 · The paper itself

Abstract

Flavobacterium psychrophilum, the causative agent of bacterial cold water disease (BCWD), is one of the leading pathogens in rainbow trout (Oncorhynchus mykiss) aquaculture. To date, there is little knowledge of the transmission kinetics of F. psychrophilum over the course of infection. In particular, how transmission is affected by host genotype and pathogen exposure dosage are not well studied. In order to fill in these knowledge gaps, we exposed two divergently selected lines of rainbow trout (ARS-Fp-R and ARS-Fp-S) to a range of dosages of F. psychrophilum (strain CSF117-10). We then measured mortality and bacterial shedding to estimate transmission risk at multiple time points since initial infection. As dosage increased, the number of fish shedding and the amount of bacteria shed increased ranging from 0% to 100% and 10

Indexed as

Bacterial SheddingFish DiseasesFlavobacteriaceae InfectionsFlavobacteriumOncorhynchus mykissAnimalsAquaculturediseasedosageflavobacteriumresistancesalmonidshedding

Identifiers

PMID39380420
PMCPMC11978924

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.