Evidence map›Paper›PMID 39380217›Full record

SynthesisJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2024

Systematic review and Meta-analysis of brain plasticity associated with electroacupuncture in experimental ischemic stroke.

X U Yingshan, W U Chunxiao, Y U Wei, Guo Hongji, L U Liming, X U Nenggui, Tang Chunzhi

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

X U YingshanCollege of Acupuncture and Massage, Shaanxi University of Chinese Medicine, Middle Section of Century Avenue, Xianyang 712046, China.
W U ChunxiaoDepartment of Encephalopathy, Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou University of Chinese Medicine, Shenzhen 518000, China.
Y U WeiDepartment of Obstetrics and Gynecology, Shenzhen Hospital of Guangzhou University of Chinese Medicine, Shenzhen 518034, China.
Guo HongjiMedical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
L U LimingMedical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
X U NengguiMedical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Tang ChunzhiMedical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.

Funding

Electroacupuncture Prevents Ferroptosis in Ischemic Stroke Through Regulating Ubiquitin Ligase NEDD4-like E3 and Inhibiting Ferritinophagy Pathway 82104978Mechanism of Acupuncture on Microglia Activation in Mice with Cerebral Ischemia-Reperfusion 23JK0410
6 · The paper itself

Abstract

objectiveTo systematically evaluate the role of electroacupuncture in maintaining brain plasticity in ischemic stroke mediated brain damage.

methodsWe searched for all relevant trials published through Oct 7, 2022 from seven databases. Metho-dological quality was assessed using the CAMARADES Risk of Bias Tool. A Meta-analysis of comparative effects was performed using Review Manager v.5.3 software.

resultsA total of 101 studies involving 2148 animals were included. For most studies, primary outcomes results of the Meta-analysis indicate that EA significantly improved ischemic stroke rat's postsynaptic density thickness [Standardized Mean Difference (

conclusionThe existing evidence suggests EA regulating ischemic stroke may be through brain plasticity. More rigorous and high quality studies should be conducted in the future.

Indexed as

ElectroacupunctureIschemic StrokeNeuronal PlasticityAnimalsBrainBrain IschemiaDisease Models, AnimalHumansRatsanimalbrain plasticityelectroacupunctureexperimental ischemic strokeMeta-analysissystematic review

Identifiers

PMID39380217
PMCPMC11462533

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.