Evidence map›Paper›PMID 39380065›Full record

ReviewStem cell research & therapy2024

Mesenchymal stromal cell therapy (REGENACIP

Sanjay Desai, Digvijay Sharma, Rajesh Srinivas, Venugopal Balaji, Vijay Thakore, Varinder Singh Bedi, Ravul Jindal, Amarnath Sugumaran, Senthilnathan Mohanasundaram, Jaideep Gogtay and 3 more

Abstract readReview
In one paragraph

Review in Stem cell research & therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sanjay DesaiSenior Consultant Vascular and Endovascular surgeon, Ramaiah Memorial Hospital, Bengaluru, India.
Digvijay SharmaHead of Department, Vascular Interventions and Surgery, Fortis Escorts Heart Institute, New Delhi, India.
Rajesh SrinivasVascular Surgeon, NH-Mazumdar-Shaw Medical Center, Bengaluru, India.
Venugopal BalajiSenior Vascular Surgeon, Apollo Hospital, Chennai, India.
Vijay ThakoreSenior Vascular Surgeon, Aadicura Super Speciality Hospitals, Vadodara, India.
Varinder Singh BediChairman & Senior Consultant, Institute of Vascular & Endovascular Sciences, Sir Ganga Ram Hospital, New Delhi, India.
Ravul JindalDirector of Vascular & Endovascular Surgery, Fortis Hospital, Mohali, India.
Amarnath SugumaranMedical Affairs, Cipla Ltd, Mumbai, India. amarnath.sugumaran@cipla.com.
Senthilnathan MohanasundaramMedical Affairs, Cipla Ltd, Mumbai, India.
Jaideep GogtayMedical Affairs, Cipla Ltd, Mumbai, India.
Pawan Kumar GuptaStempeutics Research Pvt. Ltd, Bengaluru, India.
Aniruddha BhuiyanConsultant Vascular & Endovascular Surgery, Vascular Care n Cure, Mumbai, India.
Gnaneswar AtturuHead & Senior Consultant, Department of Vascular & Endovascular Surgery, Renova Hospitals, Hyderabad, India.

Funding

Cipla Cipla
6 · The paper itself

Abstract

Chronic Limb Threatening Ischemia (CLTI) is a challenging clinical problem associated with high morbidity and mortality. Endovascular interventions have been the cornerstone of treatment whenever possible. It is estimated that CLTI represents < 10% of all Peripheral Artery Disease patients, yet 50% of the patients end up either with a major amputation of the lower limbs or die of cardiovascular causes within one year period, especially in those with unsuccessful revascularization or "no-option" CLTI. Cell-based therapeutics, especially bone marrow-derived mesenchymal stromal cells have emerged as a potential, promising, and novel alternate therapeutic modality in the management of CLTI, bolstered with positive results in numerous research, including randomized and nonrandomized trials. REGENACIP

Indexed as

IschemiaMesenchymal Stem Cell TransplantationChronic Limb-Threatening IschemiaHumansLower ExtremityMesenchymal Stem CellsPeripheral Arterial DiseaseAngiogenesisBuerger’s diseaseCritical limb ischemiaPeripheral arterial diseaseStem cell therapy

Identifiers

PMID39380065
PMCPMC11463160

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.