ArticleBMC emergency medicine2024
Clinical characteristics and toxicological spectrum analysis of 493 cases of acute poisoning in children.
Article in BMC emergency medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Analysis of risk factors for severe acute poisoning in children.Frontiers in pediatrics · 2026Article
- A clinical review of acute poisoning among pediatric individuals.European journal of medical research · 2025Article
- From Fragile Lives to Forensic Truth: Multimodal Forensic Approaches to Pediatric Homicide and Suspect Death.Diagnostics (Basel, Switzerland) · 2025Review
- Emergency Department Visits for Pediatric Poisoning in China: A 318-Case Review.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- The Impact of Comorbidities, EEG Abnormalities, and ASM Use as a Predicting Outcomes in Pediatric Status Epilepticus.Neuropsychiatric disease and treatment · 2025Article
- Machine Learning-Based Prognostic Prediction Models in Calcium Channel Blockers Poisoning.Archives of academic emergency medicine · 2025Article
- Case series: Clinical management strategies of pediatric clonazepam poisoning informed by pharmacokinetics.Science progressArticle
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Authors and funding
3 authors.
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Abstract
objectiveThis retrospective study aimed to analyze the clinical characteristics and toxicological spectrum of acute poisoning in children treated at our pediatric intensive care unit. The findings provide a basis for the treatment and prevention of acute poisoning in children.
methodsClinical data of hospitalized children aged 0 to14 years with acute poisoning, treated between January 2015 and December 2023, were collected and analyzed. The analysis included the types of poisoning, sex and age distribution of children, routes and causes of poisoning, time from poisoning to medical consultation, length of hospital stays, and treatment outcomes.
resultsAmong the 493 cases of acute poisoning in children, pesticide poisoning (n = 252, 51.1%) was the most common type, followed by medication poisoning (n = 182, 36.9%). Chemical poisoning accounted for 7.7% (n = 38), while food poisoning and inhalation of harmful gases accounted for 3.0% (n = 15) and 1.2% (n = 6), respectively. The main route of poisoning was oral ingestion (n = 477, 96.8%), while accidental ingestion accounted for a large proportion (n = 379, 79.4%), and adolescents aged 11 to 14 years accounted for 20.6% (n = 98).Apart from the predominance of girls attempting suicide by self-administering antipsychotic medications (n = 88, 75.9%) due to depression, there was no significant difference in sex distribution among other types of poisoning children. The highest incidence of poisoning except children who self-administer antipsychotic drugs occurred in children aged 1-3 years (n = 267, 54.2%) and 8-14 years (n = 135, 27.4%), with the highest proportion in the preschool age group. The average time from poisoning to medical consultation was 33.4 ± 54.9 h, and majority of children received treatment within 48 h after poisoning (n = 423, 85.8%). The overall effective treatment rate was 96.8%.
conclusionAcute poisoning in children has complex and diverse causes, with accidental ingestion being the main route. Prevention should be emphasized, including strengthening child safety education and improving parental supervision. Moreover, psychological health education is crucial for adolescents during their puberty. In the event of acute poisoning, prompt medical consultation and appropriate treatment are necessary to mitigate adverse outcomes.
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