Evidence map›Paper›PMID 39379758›Full record

ArticleJournal of hematopathology2024

Follicular dendritic cell sarcoma involving the parotid gland with expression of the melanocytic marker PRAME.

Sumayya Aslam, Ifegwu Ibe, Ying Zhang, Roksolana Demianets, Truc Tran, Ashley Gamayo, Xiaohui Zhao, Sherif A Rezk

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of hematopathology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sumayya AslamDepartment of Pathology and Laboratory Medicine, Irvine Medical Center (UCI), University of California, 101 The City Drive, Bldg. 54, Rm 4702, Orange, CA, 92868, USA.
Ifegwu IbeDepartment of Pathology and Laboratory Medicine, Irvine Medical Center (UCI), University of California, 101 The City Drive, Bldg. 54, Rm 4702, Orange, CA, 92868, USA.
Ying ZhangDepartment of Pathology and Laboratory Medicine, Irvine Medical Center (UCI), University of California, 101 The City Drive, Bldg. 54, Rm 4702, Orange, CA, 92868, USA.
Roksolana DemianetsDepartment of Pathology and Laboratory Medicine, Irvine Medical Center (UCI), University of California, 101 The City Drive, Bldg. 54, Rm 4702, Orange, CA, 92868, USA.
Truc TranDepartment of Pathology and Laboratory Medicine, Irvine Medical Center (UCI), University of California, 101 The City Drive, Bldg. 54, Rm 4702, Orange, CA, 92868, USA.
Ashley GamayoDepartment of Pathology and Laboratory Medicine, Irvine Medical Center (UCI), University of California, 101 The City Drive, Bldg. 54, Rm 4702, Orange, CA, 92868, USA.
Xiaohui ZhaoDepartment of Pathology and Laboratory Medicine, Irvine Medical Center (UCI), University of California, 101 The City Drive, Bldg. 54, Rm 4702, Orange, CA, 92868, USA.
Sherif A RezkDepartment of Pathology and Laboratory Medicine, Irvine Medical Center (UCI), University of California, 101 The City Drive, Bldg. 54, Rm 4702, Orange, CA, 92868, USA. srezk@uci.edu.ORCID http://orcid.org/0000-0003-4652-2130

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Follicular dendritic cell sarcoma is a rare mesenchymal neoplasm arising from follicular dendritic cells (FDC) of lymphoid follicles. While the majority of FDC sarcoma cases arise within lymph nodes, approximately 30% manifest in extranodal sites. Only 4 prior occurrences of intra-parotid FDC sarcomas have been documented. We are reporting a rare case of FDC of the parotid gland in a 65-year-old male with a questionable history of B-cell lymphoma. The patient underwent a right total parotidectomy and bilateral neck dissection. A diagnosis of follicular dendritic cell (FDC) sarcoma was made, with one positive intra-parotid node. The malignant cells expressed the characteristic markers for FDC sarcoma but with positivity of the melanocytic marker PRAME. This is a case of FDC sarcoma with an unusual extranodal localization in the parotid gland. Immunohistochemistry was useful in making a diagnosis although the positivity for the melanocytic marker PRAME was unusual and unreported before.

Indexed as

Antigens, NeoplasmBiomarkers, TumorDendritic Cell Sarcoma, FollicularParotid NeoplasmsAgedHumansImmunohistochemistryMaleParotid GlandAntigens, NeoplasmBiomarkers, TumorPRAME protein, humanFollicular dendritic cellsMelanomaParotid glandPRAMESarcoma

Identifiers

PMID39379758
PMCPMC11634961

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.