Evidence map›Paper›PMID 39379678›Full record

ArticleCancer causes & control : CCC2025

Clinical trial knowledge among cancer survivors in the United States: the role of health information technology.

Ted O Akhiwu, Comfort Adewunmi, Mariah Bilalaga, Joseph O Atarere, Greeshma Gaddipati, Onyema G Chido-Amajuoyi, Diamond K Eziuche, Henry Onyeaka, Hermioni L Amonoo

Abstract read
In one paragraph

Article in Cancer causes & control : CCC, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ted O AkhiwuDepartment of Medicine, MedStar Union Memorial Hospital, Baltimore, MD, USA. Ted.o.akhiwu@medstar.net.
Comfort AdewunmiDivision of Geriatrics and Gerontology, Emory University School of Medicine, Atlanta, GA, USA.
Mariah BilalagaDepartment of Medicine, MedStar Union Memorial Hospital, Baltimore, MD, USA.
Joseph O AtarereDepartment of Medicine, MedStar Union Memorial Hospital, Baltimore, MD, USA.
Greeshma GaddipatiDepartment of Medicine, MedStar Union Memorial Hospital, Baltimore, MD, USA.
Onyema G Chido-AmajuoyiUniversity of Washington/Fred Hutchinson Cancer Center, Seattle, WA, USA.
Diamond K EziucheDepartment of Public Health, National Open University, Abuja, Nigeria.
Henry OnyeakaDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Hermioni L AmonooDepartment of Psychosocial Oncology and Palliative Care, Dana-Farber Cancer Institute, Boston, MA, USA.

Funding

A Positive Psychology Intervention for Allogeneic Stem Cell Transplant Patients.K08CA251654 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI AMONOO, HERMIONI L. · 2020 to 2024
$1.3M
NCI NIH HHS K08 CA251654NIH HHS K08CA251654
6 · The paper itself

Abstract

purposeClinical trials are essential to the advancement of cancer care. However, clinical trial knowledge and participation remain critically low among adult patients with cancer. Health information technology (HIT) could play an important role in improving clinical trial knowledge and engagement among cancer survivors.

methodsWe used data from 3,794 adults who completed the 2020 Health Information National Trends Survey, 626 (16.2%) of whom were cancer survivors. We examined the prevalence of HIT use in the study population and by cancer history using chi-squared tests. We used multivariable logistic regression models to examine the impact of HIT use on clinical trial knowledge for cancer survivors and respondents with no cancer history, respectively.

resultsApproximately 63.8% of cancer survivors reported having some knowledge of clinical trials. Almost half of the cancer survivors used HIT to communicate with doctors (47.1%) and make health appointments (49.4%), 68.0% used HIT to look up health information online and 42.2% used it to check test results. In the adjusted models, the use of HIT in communicating with doctors [OR 2.79; 95% CI (1.41, 5.54)], looking up health information online [OR 2.84; 95% CI (1.04, 7.77)], and checking test results [OR 2.47; 95% CI (1.12, 5.43)] was associated with having some knowledge of clinical trials.

conclusionHIT use for engaging with the healthcare team and health information gathering is associated with higher clinical trial knowledge in cancer survivors. Given the rapid increase in mobile technology access globally and the increased use of HIT, digital technology can be leveraged to improve clinical trial knowledge and engagement among cancer survivors.

Indexed as

Cancer SurvivorsClinical Trials as TopicHealth Knowledge, Attitudes, PracticeMedical InformaticsNeoplasmsAdultAgedFemaleHumansMaleMiddle AgedSurveys and QuestionnairesUnited StatesYoung AdultClinical trial knowledgeHealth communicationHealth information technologyHealth literacy

Identifiers

PMID39379678
PMCPMC13420007

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.