Evidence map›Paper›PMID 39379478›Full record

ArticleScientific reports2024

Development and transfer learning of self-attention model for major adverse cardiovascular events prediction across hospitals.

Yunha Kim, Heejun Kang, Hyeram Seo, Heejung Choi, Minkyoung Kim, JiYe Han, Gaeun Kee, Seohyun Park, Soyoung Ko, HyoJe Jung and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Cross-cohort Generalization for Heart Disease Prediction with Explainable AI.Journal of cardiovascular translational research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yunha KimDepartment of Medical Science, Asan Medical Center, Asan Medical Institute of Convergence Science and Technology, University of Ulsan College of Medicine, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
Heejun KangDivision of Cardiology, Asan Medical Center, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
Hyeram SeoDepartment of Information Medicine, Asan Medical Center, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
Heejung ChoiDepartment of Medical Science, Asan Medical Center, Asan Medical Institute of Convergence Science and Technology, University of Ulsan College of Medicine, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
Minkyoung KimDepartment of Information Medicine, Asan Medical Center, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
JiYe HanDepartment of Information Medicine, Asan Medical Center, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
Gaeun KeeDepartment of Medical Science, Asan Medical Center, Asan Medical Institute of Convergence Science and Technology, University of Ulsan College of Medicine, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
Seohyun ParkDepartment of Medical Science, Asan Medical Center, Asan Medical Institute of Convergence Science and Technology, University of Ulsan College of Medicine, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
Soyoung KoDepartment of Medical Science, Asan Medical Center, Asan Medical Institute of Convergence Science and Technology, University of Ulsan College of Medicine, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
HyoJe JungDepartment of Medical Science, Asan Medical Center, Asan Medical Institute of Convergence Science and Technology, University of Ulsan College of Medicine, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
Byeolhee KimDepartment of Medical Science, Asan Medical Center, Asan Medical Institute of Convergence Science and Technology, University of Ulsan College of Medicine, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea.
Tae Joon Jun *Big Data Research Center, Asan Institute for Life Sciences, Asan Medical Center, 88, Olympicro 43gil, Songpagu, Seoul, 05505, Republic of Korea. taejoon@amc.seoul.kr.
Jae-Hyung Roh *Department of Internal Medicine, Chungnam National University College of Medicine, Chungnam National University Sejong Hospital, 20, Bodeum 7-Ro, Sejong-Si, Sejong, 30099, Republic of Korea.
Young-Hak Kim *Division of Cardiology, Department of Information Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Songpagu, Seoul, 05505, Republic of Korea. mdyhkim@amc.seoul.kr.

Funding

Korea Health Technology R&D Project through the Korea Health Industry Development Institute HR20C0026Korea Medical Device Development Fund grant funded by the Korea government RS-2020-KD000097
6 · The paper itself

Abstract

Predicting major adverse cardiovascular events (MACE) is crucial due to its high readmission rate and severe sequelae. Current risk scoring model of MACE are based on a few features of a patient status at a single time point. We developed a self-attention-based model to predict MACE within 3 years from time series data utilizing numerous features in electronic medical records (EMRs). In addition, we demonstrated transfer learning for hospitals with insufficient data through code mapping and feature selection by the calculated importance using Xgboost. We established operational definitions and categories for diagnoses, medications, and laboratory tests to streamline scattered codes, enhancing clinical interpretability across hospitals. This resulted in reduced feature size and improved data quality for transfer learning. The pre-trained model demonstrated an increase in AUROC after transfer learning, from 0.564 to 0.821. Furthermore, to validate the effectiveness of the predicted scores, we analyzed the data using traditional survival analysis, which confirmed an elevated hazard ratio for a group with high scores.

Indexed as

Cardiovascular DiseasesElectronic Health RecordsHospitalsAgedFemaleHumansMaleMiddle AgedRisk AssessmentRisk FactorsCardiovascular diseaseFeature selectionMulti-source dataRisk predictionTransfer learning

Identifiers

PMID39379478
PMCPMC11461710

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.