ArticleImmunity2024
Type I IFN drives unconventional IL-1β secretion in lupus monocytes.
Abstract read
In one paragraph
Article in Immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed.
- Monocyte exhaustion associated with systemic lupus erythematosus.Autoimmunity · 2026Article
- Article
- Macrophage RSAD2 Couples mtDNA Synthesis With a Self-Amplifying Inflammatory Circuit to Orchestrate Tissue Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The Variant rs2706682 at PITPNC1, Which Enhances Vehicular Secretion, Associated With Systemic Lupus Erythematosus Susceptibility in Chinese Populations.International journal of immunogenetics · 2026Article
- Review
- Whole blood exchange-lymphoplasmapheresis combined transfusion as an immunotherapy in systemic lupus erythematosus.iScience · 2026Article
- The NLRP3 inflammasome as a dynamic context-dependent regulator: mechanisms, disease progression, and therapeutic implications.Journal of translational medicine · 2026Review
- scImmuneCo: a compendium of cell-type-specific functional modules for decoding immune responses from single-cell RNA-seq data.Briefings in bioinformatics · 2026Article
- Review
- Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4): Between immune tolerance and genetic predisposition to Systemic Lupus Erythematosus (SLE).Journal of translational autoimmunity · 2026Review
- Article
- A transcriptional patient map of systemic lupus erythematosus reveals disease-related multicellular immune programs conserved between blood and kidney.bioRxiv : the preprint server for biology · 2026Article
- A systems immunology approach reveals divergent immune profiles of RSV and SARS-CoV-2 infections in infants.Science translational medicine · 2026Article
- Tubule-Derived IFN-α Promotes GSDMD-Mediated Macrophage Pyroptosis to Drive Renal Inflammation and Fibrosis Through JAK2/STAT2 Activation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- Mitochondrial DNA in systemic lupus erythematosus: pathogenic mechanisms, clinical biomarkers, and precision therapeutic strategies.Frontiers in immunology · 2026Review
- Mitochondrial DNA efflux as a potential amplifier of systemic inflammatory network rewiring in heart failure with preserved ejection fraction.Frontiers in immunology · 2026Review
- Immunopathogenesis and Therapeutics of Systemic Lupus Erythematosus: an Integrative Review.Clinical reviews in allergy & immunology · 2025Review
- Review
- cGAS-STING signaling pathway as a therapeutic target in human diseases.Chinese medical journal · 2025Review
Corrections and comments
- Commented on by
Authors and funding
19 authors.
Simone CaielliDrukier Institute for Children's Health, Weill Cornell Medicine, New York, NY, USA; Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA. Electronic address: sic2011@med.cornell.edu.
Preetha BalasubramanianDrukier Institute for Children's Health, Weill Cornell Medicine, New York, NY, USA; Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA.
Juan Rodriguez-AlcazarDrukier Institute for Children's Health, Weill Cornell Medicine, New York, NY, USA; Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA.
Uthra BalajiDrukier Institute for Children's Health, Weill Cornell Medicine, New York, NY, USA; Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA.
Lauren RobinsonDrukier Institute for Children's Health, Weill Cornell Medicine, New York, NY, USA; Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA; Division of Pediatric Rheumatology, Hospital for Special Surgery, New York, NY, USA.
Zurong WanDrukier Institute for Children's Health, Weill Cornell Medicine, New York, NY, USA; Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA.
Jeanine BaischDrukier Institute for Children's Health, Weill Cornell Medicine, New York, NY, USA; Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA.
Cynthia SmithermanDrukier Institute for Children's Health, Weill Cornell Medicine, New York, NY, USA; Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA.
Lynnette WaltersScottish Rite Hospital for Children, Dallas, TX, USA.
Paola SparaganaScottish Rite Hospital for Children, Dallas, TX, USA.
Djamel Nehar-BelaidThe Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Radu MarchesThe Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.
Lorien NassiScottish Rite Hospital for Children, Dallas, TX, USA; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA; Children's Medical Center, Dallas, TX, USA.
Katie StewartScottish Rite Hospital for Children, Dallas, TX, USA; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA; Children's Medical Center, Dallas, TX, USA.
Julie FullerScottish Rite Hospital for Children, Dallas, TX, USA; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA; Children's Medical Center, Dallas, TX, USA.
Jacques F BanchereauImmunoledge LLC, Montclair, NJ, USA.
Jinghua GuDrukier Institute for Children's Health, Weill Cornell Medicine, New York, NY, USA; Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA.
Tracey WrightScottish Rite Hospital for Children, Dallas, TX, USA; Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA; Children's Medical Center, Dallas, TX, USA.
Virginia PascualDrukier Institute for Children's Health, Weill Cornell Medicine, New York, NY, USA; Department of Pediatrics, Weill Cornell Medicine, New York, NY, USA. Electronic address: vip2021@med.cornell.edu.
Funding
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2MProject 2: The Isoform repertoire and epigenome of Pediatric SLEP50AR070594 · NIAMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI Maria Virginia Pascual · 2016 to 2026
$18.6MPrincipal ProjectU19AI144301 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI Maria Virginia Pascual · 2019 to 2026
$9.9MScientific CoreU19AI082715 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI PASCUAL, MARIA VIRGINIA · 2009 to 2018
$6.4MNCATS NIH HHS UL1 TR002384NIAID NIH HHS U19 AI082715NIAID NIH HHS U19 AI144301NIAMS NIH HHS P50 AR070594
Abstract
Opsonization of red blood cells that retain mitochondria (Mito
Indexed as
Interferon Type IInterleukin-1betaLupus Erythematosus, SystemicMonocytesNucleotidyltransferasesAdaptor Proteins, Signal TransducingCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseDEAD Box Protein 58DNA, MitochondrialFemaleHumansInflammasomesMitochondriaMyxovirus Resistance ProteinsReceptors, ImmunologicSignal TransductionAdaptor Proteins, Signal TransducingcGAS protein, humanCyclic Guanosine Monophosphate-Adenosine Monophosphate SynthaseDEAD Box Protein 58DNA, MitochondrialInflammasomesInterferon Type IInterleukin-1betaMAVS protein, humanMyxovirus Resistance ProteinsNucleotidyltransferasesReceptors, ImmunologicRIGI protein, humaninflammasomemonocytesMxANLRP3red blood cellssystemic lupus erythematosustype I interferon
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.