Evidence map›Paper›PMID 39378282›Full record

ArticleBrain and behavior2024

Can Residual Inhibition Predict the Success of Sound Enrichment Treatment for Tinnitus?

Eser Sendesen, Didem Turkyilmaz

Abstract read
In one paragraph

Article in Brain and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Notch-induced lateral inhibition compared to standard amplification lateral inhibition therapy for the treatment of chronic tinnitus: A randomised controlled trial.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Trial
  2. Brief Acoustic Tinnitus Suppression as a Diagnostic Procedure in Clinical Routine: Feasibility and Results.Journal of the Association for Research in Otolaryngology : JARO · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Eser SendesenDepartment of Audiology, Hacettepe University, Ankara, Turkey.ORCID https://orcid.org/0000-0001-6363-6071
Didem TurkyilmazDepartment of Audiology, Hacettepe University, Ankara, Turkey.ORCID https://orcid.org/0000-0001-5719-2355

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objective of this study was to investigate whether residual inhibition (RI), which provides information on the relationship between tinnitus and increased spontaneous activity in the auditory system, is a predictor for the success of sound enrichment treatment.

designTinnitus patients were divided into two groups based on whether RI was achieved (RI+) or not (RI-). All participants underwent sound enrichment. Psychosomatic measures (for tinnitus severity, discomfort, attention deficit and sleep difficulties), Tinnitus Handicap Inventory (THI), minimum masking level (MML), and tinnitus loudness level (TLL) results were compared before and at 1, 3, and 6 months after treatment. STUDY SAMPLE: Sixty-seven chronic tinnitus patients were divided into two groups based on whether RI was achieved (RI+) or not (RI-). There were 38 patients in the RI+ group and 29 in the RI- group.

resultsThere was a statistically significant difference between the groups in psychosomatic measures, THI, MML and TLL scores at the post-treatment 6 months after treatment (p <.05). There was a statistically significant decrease in psychosomatic measures, THI, MML and TLL scores during the treatment period in the RI+ group, but not in the RI- group.

conclusionRI may predict the prognosis of tinnitus treatments used in clinics to reduce the spontaneous firing rate of neurons in the central auditory system, and that RI positivity may be a predictor of treatment success in sound enrichment.

Indexed as

TinnitusAcoustic StimulationAdultAgedFemaleHumansMaleMiddle AgedNeural InhibitionPerceptual MaskingSoundTreatment Outcomeresidual inhibitionsound enrichmenttinnitustinnitus pitch

Identifiers

PMID39378282
PMCPMC11460611

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.