Evidence map›Paper›PMID 39378092›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Adolescent alcohol consumption predicted by differences in electrophysiological functional connectivity and neuroanatomy.

Alberto Del Cerro-León, Luis Fernando Antón-Toro, Danylyna Shpakivska-Bilan, Marcos Uceta, Alejandro Santos-Mayo, Pablo Cuesta, Ricardo Bruña, Luis M García-Moreno, Fernando Maestú

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Adolescent alcohol consumption predicted by differences in electrophysiological functional connectivity and neuroanatomy.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alberto Del Cerro-LeónCenter of Cognitive and Computational Neuroscience, Universidad Complutense de Madrid, Madrid 28040, Spain.ORCID 0000-0003-0630-0373
Luis Fernando Antón-ToroCenter of Cognitive and Computational Neuroscience, Universidad Complutense de Madrid, Madrid 28040, Spain.
Danylyna Shpakivska-BilanCenter of Cognitive and Computational Neuroscience, Universidad Complutense de Madrid, Madrid 28040, Spain.
Marcos UcetaCenter of Cognitive and Computational Neuroscience, Universidad Complutense de Madrid, Madrid 28040, Spain.
Alejandro Santos-MayoCenter of Cognitive and Computational Neuroscience, Universidad Complutense de Madrid, Madrid 28040, Spain.ORCID 0000-0002-5487-1608
Pablo CuestaCenter of Cognitive and Computational Neuroscience, Universidad Complutense de Madrid, Madrid 28040, Spain.
Ricardo BruñaCenter of Cognitive and Computational Neuroscience, Universidad Complutense de Madrid, Madrid 28040, Spain.ORCID 0000-0003-1007-900X
Luis M García-MorenoDepartment of Psychobiology and Methodology in Behavioral Science, Faculty of Education, Complutense University of Madrid, Madrid 28040, Spain.ORCID 0000-0002-7268-745X
Fernando MaestúCenter of Cognitive and Computational Neuroscience, Universidad Complutense de Madrid, Madrid 28040, Spain.

Funding

MISAN | Plan Nacional sobre Drogas (PNSD) 2021I075Universidad Camilo José Cela (UCJC) n/aUniversidad Complutense de Madrid (UCM) CT15/23Universidad Complutense de Madrid (UCM) CT58/21-CT59/21Universidad Complutense de Madrid (UCM) n/a
6 · The paper itself

Abstract

Alcohol consumption during adolescence has been associated with neuroanatomical abnormalities and the appearance of future disorders. However, the latest advances in this field point to the existence of risk profiles which may lead to some individuals into an early consumption. To date, some studies have established predictive models of consumption based on sociodemographic, behavioral, and anatomical-functional variables using MRI. However, the neuroimaging variables employed are usually restricted to local and hemodynamic phenomena. Given the potential of connectome approaches, and the high temporal dynamics of electrophysiology, we decided to explore the relationship between future alcohol consumption and electrophysiological connectivity measured by MEG in a cohort of 83 individuals aged 14 to 16. As a result, we found a positive correlation between alcohol consumption and the functional connectivity in frontal, parietal, and frontoparietal connections. Once this relationship was described, multivariate linear regression analyses were used to evaluate the predictive capacity of functional connectivity in conjunction with other neuroanatomical and behavioral variables described in the literature. Finally, the multivariate linear regression analysis determined the importance of anatomical and functional variables in the prediction of alcohol consumption but failed to find associations with impulsivity, sensation seeking, and executive function scales. In conclusion, the predictive traits obtained in these models were closely associated with changes occurring during adolescence, suggesting the existence of different paths in neurodevelopment that have the potential to influence adolescents' relationship with alcohol consumption.

Indexed as

Underage DrinkingAdolescentAlcohol DrinkingBrainConnectomeFemaleHumansMagnetic Resonance ImagingMalealcoholelectrophysiologyfunctional connectivityMEGMRI

Identifiers

PMID39378092
PMCPMC11494299

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.