Evidence map›Paper›PMID 39378088›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Methionine-rich domains emerge as facilitators of copper recruitment in detoxification systems.

Umberto Contaldo, Dylan Savant-Aira, Alexandra Vergnes, Jérôme Becam, Frédéric Biaso, Marianne Ilbert, Laurent Aussel, Benjamin Ezraty, Elisabeth Lojou, Ievgen Mazurenko

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Exploring the role of oxidative defects in polyethylene binding and degradation by a Rhodococcus opacus R7 multicopper oxidase: a computational perspective.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Umberto ContaldoAix Marseille University, CNRS, BIP - UMR 7281, IMM - FR3479, 13402 Marseille, France.ORCID 0000-0002-1700-170X
Dylan Savant-AiraAix Marseille University, CNRS, BIP - UMR 7281, IMM - FR3479, 13402 Marseille, France.
Alexandra VergnesAix Marseille University, CNRS, LCB - UMR 7283, IMM - FR3479, 13402 Marseille, France.ORCID 0000-0001-6745-6633
Jérôme BecamAix Marseille University, CNRS, LCB - UMR 7283, IMM - FR3479, 13402 Marseille, France.
Frédéric BiasoAix Marseille University, CNRS, BIP - UMR 7281, IMM - FR3479, 13402 Marseille, France.
Marianne IlbertAix Marseille University, CNRS, BIP - UMR 7281, IMM - FR3479, 13402 Marseille, France.ORCID 0000-0002-9070-2334
Laurent AusselAix Marseille University, CNRS, LCB - UMR 7283, IMM - FR3479, 13402 Marseille, France.ORCID 0000-0001-5239-4556
Benjamin EzratyAix Marseille University, CNRS, LCB - UMR 7283, IMM - FR3479, 13402 Marseille, France.ORCID 0000-0003-3818-6907
Elisabeth LojouAix Marseille University, CNRS, BIP - UMR 7281, IMM - FR3479, 13402 Marseille, France.ORCID 0000-0003-2593-4670
Ievgen MazurenkoAix Marseille University, CNRS, BIP - UMR 7281, IMM - FR3479, 13402 Marseille, France.ORCID 0000-0003-2563-3130

Funding

Agence Nationale de la Recherche (ANR) ANR-19-CE44-0018Agence Nationale de la Recherche (ANR) ANR-21-CE44-0024Aix-Marseille Université (AMU) AMX-21-PEP-001
6 · The paper itself

Abstract

Copper homeostasis mechanisms are critical for bacterial resistance to copper-induced stress. The

Indexed as

CopperEscherichia coliEscherichia coli ProteinsMethionineBinding SitesOxidation-ReductionOxidoreductasesProtein DomainsCoppercueO protein, E coliEscherichia coli ProteinsMethionineOxidoreductasescopper homeostasisCu+ oxidationelectrochemistrymethionine-rich domainmulticopper oxidase CueO

Identifiers

PMID39378088
PMCPMC11494321

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.