Evidence map›Paper›PMID 39377995›Full record

ArticleInternational urology and nephrology2025

Collagen fleece grafting for surgical treatment of patients with mild to severe peyronie's curvatures.

Radion Garaz, Bastian Amend, Arnulf Stenzl, Jens Bedke, Jörg Hennenlotter, Alexander Rochwarger, Christian M Schürch, Igor Tsaur, Steffen Rausch

Abstract read
In one paragraph

Article in International urology and nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Radion GarazDepartment of Urology, Eberhard Karls University of Tübingen, Hoppe-Seyler-Straße 3, 72076, Tübingen, Germany. radion.garaz@med.uni-tuebingen.de.ORCID http://orcid.org/0000-0002-3473-4446
Bastian AmendDepartment of Urology, Eberhard Karls University of Tübingen, Hoppe-Seyler-Straße 3, 72076, Tübingen, Germany.
Arnulf StenzlDepartment of Urology, Eberhard Karls University of Tübingen, Hoppe-Seyler-Straße 3, 72076, Tübingen, Germany.
Jens BedkeDepartment of Urology and Transplantation Surgery, Stuttgart Hospital, Stuttgart, Germany.
Jörg HennenlotterDepartment of Urology, Eberhard Karls University of Tübingen, Hoppe-Seyler-Straße 3, 72076, Tübingen, Germany.
Alexander RochwargerDepartment of Pathology and Neuropathology, Eberhard Karls University of Tübingen, Tübingen, Germany.
Christian M SchürchDepartment of Pathology and Neuropathology, Eberhard Karls University of Tübingen, Tübingen, Germany.
Igor TsaurDepartment of Urology, Eberhard Karls University of Tübingen, Hoppe-Seyler-Straße 3, 72076, Tübingen, Germany.
Steffen RauschDepartment of Urology, Eberhard Karls University of Tübingen, Hoppe-Seyler-Straße 3, 72076, Tübingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCollagen fleece grafting (CFG) is the recommended treatment for severe Peyronie's disease (PD) curvature (> 60°), but its efficacy in mild/moderate curvatures remains uncertain. This study evaluated CFG in patients with mild/moderate curvatures (< 60°) at risk of penile shortening or symptomatic plaque.

methodsA retrospective review was conducted on patients who underwent surgical treatment for PD using plaque incision or partial plaque excision and CFG. Clinical parameters and complications were reviewed. Subgroup analysis was performed on patients with curvatures of > 60° and curvatures ≤ 60°.

results89 patients with a median age of 59 years and a median curvature of 70 (20-90)° were identified. Dorsal curvature was predominant in 66% of cases, followed by lateral (16%), ventral (8%), and complex curvatures (10%). Partial plaque excision was performed in 98% of patients, with an average grafting area of 2.1 cm

conclusionsEarly postoperative outcomes and complication rates following plaque incision or partial plaque excision and grafting with CFG were comparable in patients with mild/moderate and severe PD deformities. The technique may be a viable option with a similar risk profile for achieving penile straightening in selected PD cases, particularly when plication is not feasible.

Indexed as

CollagenPenile IndurationPenisAdultAgedAged, 80 and overHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesSeverity of Illness IndexTreatment OutcomeUrologic Surgical Procedures, MaleYoung AdultCollagenGraftingInduratio penis plasticaPlaque incisionTachoSil

Identifiers

PMID39377995
PMCPMC11772538

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.