Evidence map›Paper›PMID 39377970›Full record

ArticleEJNMMI research2024

[

Philipp Backhaus, Keith S Pentlow, Alan L Ho, Audrey Mauguen, James A Fagin, Naga Vara Kishore Pillarsetty, Serge K Lyashchenko, Eva Burnazi, Ronald A Ghossein, Shalini Chhabra and 6 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03196518 (PET Imaging of Thyroid Tissue Expressing Sodium-iodine Symporter Using the New Tracer 18F-tetrafluoroborate), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03196518 naactive not recruitingnot on this map

PET Imaging of Thyroid Tissue Expressing Sodium-iodine Symporter Using the New Tracer 18F-tetrafluoroborate (18F-TFB)

TypeinterventionalSponsorMemorial Sloan Kettering Cancer CenterRan2017 to 2027Enrolled5ConditionsThyroid CancerArmsPET Imaging, 18F-tetrafluoroborate (18F-TFB)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Philipp BackhausMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, P.O. Box 77, New York, NY, 10065, USA.ORCID http://orcid.org/0000-0003-4164-4104
Keith S PentlowDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Alan L HoDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Audrey MauguenDepartment of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
James A FaginDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Naga Vara Kishore PillarsettyMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, P.O. Box 77, New York, NY, 10065, USA.
Serge K LyashchenkoMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, P.O. Box 77, New York, NY, 10065, USA.
Eva BurnaziDepartment of Radiology, Weill Cornell Medical College, New York, NY, USA.
Ronald A GhosseinDepartment of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Shalini ChhabraMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, P.O. Box 77, New York, NY, 10065, USA.
Murad AbusamraMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, P.O. Box 77, New York, NY, 10065, USA.
Steven M LarsonMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, P.O. Box 77, New York, NY, 10065, USA.
Heiko SchöderMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, P.O. Box 77, New York, NY, 10065, USA.
Joseph O'DonoghueDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Wolfgang WeberDepartment of Nuclear Medicine, Technical University Munich, Munich, Germany.
Ravinder K GrewalMolecular Imaging and Therapy Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, P.O. Box 77, New York, NY, 10065, USA. grewalr@mskcc.org.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
SPORE in Thyroid CancerP50CA172012 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI FAGIN, JAMES A · 2014 to 2018
$10.3M
124I-NaI PET: Building block for precision medicine in metastatic thyroid cancerR01CA201250 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI HUMM, JOHN L, LARSON, STEVEN MARK · 2016 to 2020
$3.5M
Improving efficacy of radioiodine treatment of thyroid cancerR01CA249663 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI FAGIN, JAMES A, HO, ALAN L. · 2021 to 2025
$2.3M
NCI NIH HHS 5 P50 CA172012NCI NIH HHS CA201250NCI NIH HHS P30 CA008748NCI NIH HHS P50 CA172012NCI NIH HHS R01 CA201250NCI NIH HHS R01 CA249663
6 · The paper itself

Abstract

backgroundFluorine 18-labelled tetrafluoroborate ([

methodsFive patients were included in a prospective study. All patients received PET/CT 1 h after injection of 356 ± 12 MBq [

resultsThree patients had poorly differentiated thyroid cancer and received trametinib in a redifferentiation trial. Two patients had papillary thyroid cancer and did not receive redifferentiation therapy. Of the 33 lesions seen before/without redifferentiation therapy, 19 (58%) were visible on [

conclusion[ TRIAL REGISTRATION NUMBER: NCT03196518, registered on June 22, 2017.

Indexed as

[124I]iodine[18F]TFBPET/CTRedifferentiationThyroid cancer

Identifiers

PMID39377970
PMCPMC11461403

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.