Evidence map›Paper›PMID 39377875›Full record

ReviewDrug delivery and translational research2025

Clinical translation and landscape of silver nanoparticles.

Manuel Dias, Rui Zhang, Twan Lammers, Roger M Pallares

Abstract readReview
In one paragraph

Review in Drug delivery and translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Clinical translation and landscape of copper nanoparticles.Drug delivery and translational research · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
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  12. Review
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  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Manuel DiasInstitute for Experimental Molecular Imaging, RWTH Aachen University Hospital, 52074, Aachen, Germany.
Rui ZhangInstitute for Experimental Molecular Imaging, RWTH Aachen University Hospital, 52074, Aachen, Germany.
Twan LammersInstitute for Experimental Molecular Imaging, RWTH Aachen University Hospital, 52074, Aachen, Germany.
Roger M PallaresInstitute for Experimental Molecular Imaging, RWTH Aachen University Hospital, 52074, Aachen, Germany. rmoltopallar@ukaachen.de.ORCID 0000-0001-7423-8706

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite being clinically used for over a century, the benefits of silver nanoparticles are perennially under debate and dispute. In the last two decades, a revived interest in their therapeutic applications has resulted in a few new formulations transitioning into clinical trials. These metal nanomedicines are used in concrete applications that are defined by the physicochemical and biological features of the silver nanoconstructs, as well as their biodistribution profiles. Examples of these applications are topical antibacterial and antiviral therapies and wound healing, as these avoid concerns regarding the long-term accumulation of the nanomedicines in fenestrated organs after intravenous administration. Here, we discuss the current landscape of silver nanoparticles, and critically analyze the characteristics that endowed their transition and use in clinical settings.

Indexed as

Metal NanoparticlesSilverAnimalsAnti-Bacterial AgentsHumansNanomedicineTissue DistributionWound HealingAnti-Bacterial AgentsSilverAntimicrobialClinical trialsNanomedicineSilver nanoconstructsSilver nanoparticles

Identifiers

PMID39377875
PMCPMC11782377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.