Evidence map›Paper›PMID 39377799›Full record

ArticleClinical oral investigations2024

Preventing dentin erosion with silver diamine fluoride and salivary pellicle: an in vitro study.

Darren Dhananthat Chawhuaveang, Walter Yu-Hang Lam, Chun-Hung Chu, Ollie Yiru Yu

Abstract read
In one paragraph

Article in Clinical oral investigations, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Darren Dhananthat ChawhuaveangFaculty of Dentistry, The University of Hong Kong, 3B12, Prince Philip Dental Hospital, 34 Hospital Road, Hong Kong SAR, 999077, China.
Walter Yu-Hang LamFaculty of Dentistry, The University of Hong Kong, 3B12, Prince Philip Dental Hospital, 34 Hospital Road, Hong Kong SAR, 999077, China.
Chun-Hung ChuFaculty of Dentistry, The University of Hong Kong, 3B12, Prince Philip Dental Hospital, 34 Hospital Road, Hong Kong SAR, 999077, China.
Ollie Yiru YuFaculty of Dentistry, The University of Hong Kong, 3B12, Prince Philip Dental Hospital, 34 Hospital Road, Hong Kong SAR, 999077, China. ollieyu@hku.hk.

Funding

General Research Fund of Research Grants Council of Hong Kong SAR, China 17100820
6 · The paper itself

Abstract

objectivesTo investigate the preventive and discoloring effects of a single and two weekly applications of 38% silver diamine fluoride (SDF) against dentin erosion. MATERIALS AND

methods180 dentin blocks were divided into four groups. Group 1 (SDF2) received two weekly applications of 38% SDF. Group 2 (SDF1) received a single application of 38% SDF. Group 3 (SNF) received a daily application of stannous chloride/amine fluoride/sodium fluoride (standard of care for dental erosion). Group 4 (DW) received a daily application of deionized water. The treated blocks were subjected to a 14-day erosive challenge. Crystal characteristics, elemental composition, surface morphology, percentage of surface microhardness loss (%SMHL), surface loss, and color change (ΔE) were investigated using X-ray diffraction (XRD), energy-dispersive spectrometry (EDS), scanning electron microscopy (SEM), hardness testing, profilometry, and digital spectrophotometry, respectively.

resultsXRD and EDS showed dentin surfaces had silver compounds in SDF2 and SDF1, and stannous chloride in SNF. SEM revealed less dentin demineralization with tubular occlusion in SDF2, SDF1, and SNF, but severe demineralization in DW. The %SMHL of SDF2, SDF1, SNF, and DW were 10.8 ± 2.1, 15.7 ± 2.1, 17.9 ± 2.1, and 28.7 ± 2.0 (SDF2 < SDF1 < SNF < DW, p < 0.05). Surface loss (µm) of SDF2, SDF1, SNF, and DW were 5.0 ± 0.6, 6.0 ± 0.6, 6.0 ± 0.7, and 9.0 ± 0.5 (SDF2 < SDF1 = SNF < DW, p < 0.001). ΔE of SDF2, SDF1, SNF, and DW were 26.0 ± 3.4, 12.1 ± 3.8, 6.9 ± 3.5, and 3.9 ± 3.6 (SDF2 > SDF1 > SNF = DW, p < 0.001).

conclusion38% SDF with two weekly applications provided better preventive effects against dentin erosion, but it might discolor dentin. CLINICAL RELEVANCE: The increased 38% SDF application showed a better anti-erosive potential against dentin erosion. However, SDF caused black staining on the dentin.

Indexed as

Fluorides, TopicalMicroscopy, Electron, ScanningQuaternary Ammonium CompoundsSilver CompoundsTooth ErosionX-Ray DiffractionDentinHardnessHumansIn Vitro TechniquesSalivaSpectrometry, X-Ray EmissionSpectrophotometrySurface PropertiesTin CompoundsFluorides, TopicalQuaternary Ammonium CompoundsSilver Compoundssilver diamine fluoridestannous chlorideTin CompoundsDental erosionDentinFluorideRemineralizationSalivary pellicleSilver diamine fluoride

Identifiers

PMID39377799
PMCPMC11461690

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.