Evidence map›Paper›PMID 39377529›Full record

ArticleThe Journal of the Acoustical Society of America2024

Detection of mild sensory hearing loss using a joint reflection-distortion otoacoustic emission profile.

Carolina Abdala, Tricia Benjamin, Samantha Stiepan, Ping Luo, Christopher A Shera

Abstract read
In one paragraph

Article in The Journal of the Acoustical Society of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carolina AbdalaCaruso Department of Otolaryngology, Keck School of Medicine, University of Southern California, 1640 Marengo Avenue, Suite 326, Los Angeles, California 90033, USA.
Tricia BenjaminCaruso Department of Otolaryngology, Keck School of Medicine, University of Southern California, 1640 Marengo Avenue, Suite 326, Los Angeles, California 90033, USA.
Samantha StiepanCaruso Department of Otolaryngology, Keck School of Medicine, University of Southern California, 1640 Marengo Avenue, Suite 326, Los Angeles, California 90033, USA.
Ping LuoCaruso Department of Otolaryngology, Keck School of Medicine, University of Southern California, 1640 Marengo Avenue, Suite 326, Los Angeles, California 90033, USA.
Christopher A SheraCaruso Department of Otolaryngology, Keck School of Medicine, University of Southern California, 1640 Marengo Avenue, Suite 326, Los Angeles, California 90033, USA.ORCID 0000-0002-5939-2710

Funding

Training in Hearing & Communication NeuroscienceT32DC009975 · NIDCD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Christopher A Shera · 2009 to 2026
$5.0M
Advanced Detection and Differential Diagnosis of Hearing Loss Using Otoacoustic EmissionsR01DC018307 · NIDCD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ABDALA, CAROLINA, SHERA, CHRISTOPHER A · 2020 to 2025
$2.8M
NIDCD NIH HHS R01 DC018307NIDCD NIH HHS T32 DC009975
6 · The paper itself

Abstract

Measuring and analyzing both nonlinear-distortion and linear-reflection otoacoustic emissions (OAEs) combined creates what we have termed a "joint-OAE profile." Here, we test whether these two classes of emissions have different sensitivities to hearing loss and whether our joint-OAE profile can detect mild-moderate hearing loss better than conventional OAE protocols have. 2f1-f2 distortion-product OAEs and stimulus-frequency OAEs were evoked with rapidly sweeping tones in 300 normal and impaired ears. Metrics included OAE amplitude for fixed-level stimuli as well as slope and compression features derived from OAE input/output functions. Results show that mild-moderate hearing loss impacts distortion and reflection emissions differently. Clinical decision theory was applied using OAE metrics to classify all ears as either normal-hearing or hearing-impaired. Our best OAE classifiers achieved 90% or better hit rates (with false positive rates of 5%-10%) for mild hearing loss, across a nearly five-octave range. In summary, results suggest that distortion and reflection emissions have distinct sensitivities to hearing loss, which supports the use of a joint-OAE approach for diagnosis. Results also indicate that analyzing both reflection and distortion OAEs together to detect mild hearing loss produces outstanding accuracy across the frequency range, exceeding that achieved by conventional OAE protocols.

Indexed as

Acoustic StimulationOtoacoustic Emissions, SpontaneousAdultAgedAudiometry, Pure-ToneAuditory ThresholdCase-Control StudiesFemaleHearing Loss, SensorineuralHumansMaleMiddle AgedNonlinear DynamicsPredictive Value of TestsSeverity of Illness IndexYoung Adult

Identifiers

PMID39377529
PMCPMC11464069

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.