Evidence map›Paper›PMID 39377505›Full record

ArticlePathologica2024

Digital transition in pathology lab: a survey from the Lombardy region.

Elisa Belloni, Emanuela Bonoldi, Giorgio Bovo, Sabrina Buoro, Michele Cerati, Fulvia Milena Cribiú, Emanuele Dainese, Alessandro Del Gobbo, Mattia Facchetti, Andrea Gianatti and 9 more

Abstract read
In one paragraph

Article in Pathologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Elisa Belloni *Department of Medicine and Surgery, Pathology, IRCCS Fondazione San Gerardo dei Tintori, University of Milano-Bicocca, Italy.
Emanuela BonoldiDepartment of Pathology, Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Giorgio BovoPathology, Vimercate Hospital, ASST-Brianza, Vimercate, Italy.
Sabrina BuoroCentro Regionale di Coordinamento della Medicina di Laboratorio, Milan, Italy.
Michele CeratiUnit of Pathology, Department of Medicine and Technological Innovation, University of Insubria, ASST Sette Laghi, Varese, Italy.
Fulvia Milena CribiúPathology Unit, ASST Bergamo ovest, Treviglio (BG), Italy.
Emanuele DaineseSurgical Pathology Division, Department of Oncology, ASST Lecco, "A. Manzoni" Hospital, Lecco, Italy.
Alessandro Del GobboDivision of Pathology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Mattia FacchettiDepartment of Pathology, ASST Spedali Civili, Brescia, Italy.
Andrea GianattiDepartment of Pathology, ASST Papa Giovanni XXIII, Bergamo, Italy.
Umberto GianelliDepartment of Health Sciences, Università degli Studi di Milano, Milan, Italy; S.C. di Anatomia Patologica, ASST- Santi Paolo e Carlo, Milan, Italy.
Paolo GiuntaPathology Unit, Melegnano and Martesana ASST, Vizzolo Predabissi, Italy.
Vincenzo L'ImperioDepartment of Medicine and Surgery, Pathology, IRCCS Fondazione San Gerardo dei Tintori, University of Milano-Bicocca, Italy.
Massimo Milione1st Pathology Division, Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
Manuela NebuloniPathology Unit, ASST Fatebenefratelli Sacco, Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy.
Fabio PagniDepartment of Medicine and Surgery, Pathology, IRCCS Fondazione San Gerardo dei Tintori, University of Milano-Bicocca, Italy.
Marco PaulliDipartimento di scienze clinico-chirurgiche, diagnostiche e pediatriche - Università di Pavia, Pavia, Italy;S.C. Anatomia Patologica, Fondazione IRCCS Policlinico di Pavia, Pavia, Italy.
Antonella PigaDepartment of Oncology and Hemato-Oncology (DIPO), University of Milan, Italy.
Fabio Pasotti *Centro Regionale di Coordinamento della Medicina di Laboratorio, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Digital pathology is an opportunity to revise the routine and old artisanal workflow, moving to standard operating procedures, quality control and reproducibility. Here the results of a survey promoted by the Coordinamento della Medicina di Laboratorio (CRC Med Lab) of the Lombardy region in Italy are reported to shed light on the current situation of digital adoption in the country. Methods: The survey composed of 58 questions was sent to 60 pathology laboratories. The results were collected and most significant answers were reported and discussed. Results: Answers were received from 57 (95%) laboratories, a minority organized in spoke-hub networks (16%) with a centralized processing phase (11%). Hybrid manual/computer-assisted traceability was prevalent (36%), with QR/barcode labeling starting within the pathology lab (23%). Different laboratory information systems (LIS) were employed, mostly with alert functions and/or multimedial file attachments (56% and 46%, respectively). The majority opted for a semi-automated tracking management (44, 77%) and 18 centers (32%) were partly digitizing the routine (¾ scanning < 25% of slides). Whole slide images were retained for 3.7 years in average; in-house blocks/slides archiving was still preferred (30, 53%), with 1838 (±1551) and 1798 (±1950) days (5 years) internal permanence for blocks and slides that are stored in out-source (mean turnaround time for return on-demand 3.7±2.1, range 1-10 days). Conclusions: The advantages of digital pathology must be balanced against the challenges faced in the structural revision of the pathology workflow. This regional scouting can represent the foundation to build an efficient and connected digital pathology system in the territory.

Indexed as

WorkflowClinical Laboratory Information SystemsHumansItalyLaboratories, ClinicalPathology, ClinicalQuality ControlReproducibility of ResultsSurveys and Questionnairesarchivesdigital pathologypre-analytictraceabilitywhole slide images

Identifiers

PMID39377505
PMCPMC11460148

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.