ArticleFrontiers in public health2024
Evaluation of potential human health risks associated with Li and their relationship with Na, K, Mg, and Ca in Romania's nationwide drinking water.
Article in Frontiers in public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Organ-Based Accumulation, Translocation, and Associated Health Risk of Al, Ni, and Zn in Tomatoes, Peppers, Eggplants, Cucumbers, and Corn from an Industrial Zone in Düzce, Türkiye.Foods (Basel, Switzerland) · 2026Article
- Lithium exposure causes ferroptosis to induce unexplained miscarriage through non-canonical MBOAT1 pathway.Nature communications · 2025Article
- Comprehensive hydrogeochemical characterization and seasonal water quality index analysis for sustainable groundwater management in Valliyur region, Southern Tamil Nadu, India.Scientific reports · 2025Article
- Lithium-Occurrence and Exposure-A Review.Toxics · 2025Review
- Heavy Metal Health Risk Assessment inPlants (Basel, Switzerland) · 2025Article
- Recycling Lithium-Ion Batteries-Technologies, Environmental, Human Health, and Economic Issues-Mini-Systematic Literature Review.Membranes · 2024Review
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Authors and funding
4 authors.
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Abstract
Background: Increasing lithium (Li) demand worldwide due to its properties and role in renewable energy will raise water reservoir pollution and side effects on human health. Divergent results regarding Li concentration in water and affective disorders are found in the literature, which is why regional reports are expected. Objective: The present study evaluated the occurrence and human health risks resulting from oral exposure, respectively, and the relationship between alkali metals (Li, Na, and K) and minerals (Mg, Ca) in balanced purified water (bottled) and spring water. Methods: The ICP-MS technique was used to measure a national database with 53 bottled and 42 spring water samples randomly selected. One-way ANOVA, Pearson correlation, and HCA analysis were applied to assess the possible relationship between metals in water. The possible side effects of Li poisoning of water resources on human health have been evaluated using the Estimated Daily Intake Index (EDI) and Total Hazard Quotient (THQ). Results: The toxic metals (As, Hg, and Pb) were measured, and the results indicate values above the detection limit of 22.3% of samples in the case of lead but not exceeding the safety limits. Depending on the water sources, such as bottled and spring water, the Li concentration varied between 0.06-1,557 and 0.09-984% μg/L. We found a strong positive correlation between Li and Na and Mg, varying between bottled and spring waters ( Conclusion: We can conclude that water is safe based on the Li concentration found in drinking water and supported by a gap in strict regulations regarding human Li ingestion. The present study can serve decision-makers and represent a starting database with metals of interest for further clinical studies. Decision-makers can also use it to find solutions for sustainable management of clean and safe drinking water.
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