Evidence map›Paper›PMID 39376983›Full record

ArticleFrontiers in oncology2024

Toward standardized brain tumor tissue processing protocols in neuro-oncology: a perspective for gliomas and beyond.

Analiz Rodriguez, Manmeet S Ahluwalia, Chetan Bettegowda, Henry Brem, Bob S Carter, Susan Chang, Sunit Das, Charles Eberhart, Tomas Garzon-Muvdi, Costas G Hadjipanayis and 13 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Analiz RodriguezDepartment of Neurosurgery, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, United States.
Manmeet S AhluwaliaDepartment of Medical Oncology, Miami Cancer Institute, Baptist Health South Florida, Miami, FL, United States.
Chetan BettegowdaDepartment of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD, United States.
Henry BremDepartment of Neurosurgery, Johns Hopkins Hospital, Baltimore, MD, United States.
Bob S CarterDepartment of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Susan ChangDivision of Neuro-Oncology, Department of Neurosurgery, University of California San Francisco, San Francisco, CA, United States.
Sunit DasDivision of Neurosurgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Charles EberhartDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Tomas Garzon-MuvdiDepartment of Neurosurgery, Emory University, Atlanta, GA, United States.
Costas G HadjipanayisDepartment of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States.
Cynthia HawkinsDivision of Pathology, Hospital for Sick Children, Toronto, ON, Canada.
Thomas S JacquesDevelopmental Biology and Cancer Programme, UCL GOS Institute of Child Health and Department of Histopathology, Great Ormond Street Hospital NHS Foundation Trust, London, United Kingdom.
Alexander A KhalessiDepartment of Radiology and Neurosciences, Don and Karen Cohn Chancellor's Endowed Chair of Neurological Surgery, University of California, San Diego, San Diego, CA, United States.
Michael W McDermottDivision of Neurosurgery, Miami Neuroscience Institute, Miami, FL, United States.
Tom MikkelsenDepartment of Neurosurgery, Hermelin Brain Tumor Center, Henry Ford Health System, Detroit, MI, United States.
Brent A OrrDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, United States.
Joanna J PhillipsDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.
Mark RosenblumDepartment of Neurosurgery, Omics Laboratory, Hermelin Brain Tumor Center, Henry Ford Health System, Detroit, MI, United States.
William J SheltonDepartment of Neurosurgery, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, United States.
David A SolomonDivision of Neuropathology, Department of Pathology and Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, United States.
Andreas von DeimlingDepartment of Neuropathology, Institute of Pathology, Ruprecht-Karls-University of Heidelberg, Heidelberg, Germany.
Graeme F WoodworthDepartment of Neurosurgery, University of Maryland School of Medicine, Baltimore, MD, United States.
James T RutkaDivision of Neurosurgery, Chair Emeritus, Hospital for Sick Children, Toronto, ON, Canada.

Funding

The Center for Research, Health, and Social JusticeP50MD017319 · NIMHD · UNIV OF ARKANSAS FOR MED SCIS · PI FAGAN, PEBBLES · 2021 to 2025
$21.9M
Development of immunocompetent melanoma brain metastases organoidsR03CA289645 · NCI · UNIV OF ARKANSAS FOR MED SCIS · PI RODRIGUEZ, ANALIZ · 2024 to 2025
$153k
NCI NIH HHS R03 CA289645NIMHD NIH HHS P50 MD017319
6 · The paper itself

Abstract

Implementation of standardized protocols in neurooncology during the surgical resection of brain tumors is needed to advance the clinical treatment paradigms that use tissue for diagnosis, prognosis, bio-banking, and treatment. Currently recommendations on intraoperative tissue procurement only exist for diffuse gliomas but management of other brain tumor subtypes can also benefit from these protocols. Fresh tissue from surgical resection can now be used for intraoperative diagnostics and functional precision medicine assays. A multidisciplinary neuro-oncology perspective is critical to develop the best avenues for practical standardization. This perspective from the multidisciplinary Oncology Tissue Advisory Board (OTAB) discusses current advances, future directions, and the imperative of adopting standardized protocols for diverse brain tumor entities. There is a growing need for consistent operating room practices to enhance patient care, streamline research efforts, and optimize outcomes.

Indexed as

biobankbrain tumorsgliomasprecision medicinetissue processing

Identifiers

PMID39376983
PMCPMC11456923

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.