Evidence map›Paper›PMID 39376632›Full record

ArticleFrontiers in cell and developmental biology2024

Poly (A) binding protein 2 is critical for stem cell differentiation during regeneration in the planarian

Namita Mukundan, Nivedita Hariharan, Vidyanand Sasidharan, Vairavan Lakshmanan, Dasaradhi Palakodeti, Colin Jamora

Abstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Namita MukundanIntegrative Chemical Biology (ICB), Institute for Stem Cell Science and Regenerative Medicine, Bangalore, India.
Nivedita HariharanIntegrative Chemical Biology (ICB), Institute for Stem Cell Science and Regenerative Medicine, Bangalore, India.
Vidyanand SasidharanStowers Institute for Medical Research, Kansas City, MO, United States.
Vairavan LakshmananIntegrative Chemical Biology (ICB), Institute for Stem Cell Science and Regenerative Medicine, Bangalore, India.
Dasaradhi PalakodetiIntegrative Chemical Biology (ICB), Institute for Stem Cell Science and Regenerative Medicine, Bangalore, India.
Colin JamoraIntegrative Chemical Biology (ICB), Institute for Stem Cell Science and Regenerative Medicine, Bangalore, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-transcriptional regulation has emerged as a key mechanism for regulating stem cell renewal and differentiation, which is essential for understanding tissue regeneration and homeostasis. Poly(A)-binding proteins are a family of RNA-binding proteins that play a vital role in post-transcriptional regulation by controlling mRNA stability and protein synthesis. The involvement of poly(A) binding proteins in a wide range of cellular functions is increasingly being investigated. In this study, we used the regenerative model planarian organism

Indexed as

differentiationplanariapoly A binding proteinpost transcriptional regulationregenerationstem cell

Identifiers

PMID39376632
PMCPMC11456742

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.