Evidence map›Paper›PMID 39376564›Full record

ArticleFrontiers in immunology2024

Increased neutrophil counts are associated with poor overall survival in patients with colorectal cancer: a five-year retrospective analysis.

Libia Alejandra Garcia-Flores, María Teresa Dawid De Vera, Jesus Pilo, Alejandro Rego, Gema Gomez-Casado, Isabel Arranz-Salas, Isabel Hierro Martín, Julia Alcaide, Esperanza Torres, Almudena Ortega-Gomez and 2 more

Erratum issuedAbstract read
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Libia Alejandra Garcia-Flores *Department of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, Málaga, Spain.
María Teresa Dawid De Vera *Unidad de Gestión Clínica Intercentros (UGCI) de Anatomía Patológica, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Universitario Virgen de la Victoria, Universidad de Málaga, Málaga, Spain.
Jesus PiloDepartment of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, Málaga, Spain.
Alejandro RegoDepartment of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, Málaga, Spain.
Gema Gomez-CasadoDepartment of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, Málaga, Spain.
Isabel Arranz-SalasUnidad de Gestión Clínica Intercentros (UGCI) de Anatomía Patológica, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Universitario Virgen de la Victoria, Universidad de Málaga, Málaga, Spain.
Isabel Hierro MartínUnidad de Gestión Clínica Intercentros (UGCI) de Anatomía Patológica, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Universitario Virgen de la Victoria, Universidad de Málaga, Málaga, Spain.
Julia AlcaideMedical Oncology Service, Hospital Regional Universitario de Málaga, Biomedical Research Institute of Malaga (IBIMA), Málaga, Spain.
Esperanza TorresUnidad de Gestión Clínica Intercentros (UGCI) de Oncología Médica, Instituto de Investigación Biomédica de Málaga (IBIMA), Hospital Universitario Virgen de la Victoria, Málaga, Spain.
Almudena Ortega-GomezDepartment of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, Málaga, Spain.
Hatim Boughanem *Department of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, Málaga, Spain.
Manuel Macias-Gonzalez *Department of Endocrinology and Nutrition, Virgen de la Victoria University Hospital, Málaga, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Colorectal cancer (CRC) continues to be a major health concern in today's world. Despite conflictive findings, evidence supports systemic inflammation's impact on CRC patients' survival rates. Therefore, this study aims to assess the prognostic role of the innate immune system in patients with CRC. Method: A total of 449 patients were included, with a 5-year follow-up period, and absolute neutrophil counts and their related ratios were measured. Results: The non-survival group had increased levels of white blood cells, neutrophils (both Conclusion: This study offers comprehensive insights into the immune factors that impact the prognosis of CRC, emphasizing the need for personalized prognostic tools.

Indexed as

Colorectal NeoplasmsNeutrophilsAgedFemaleHumansLeukocyte CountMaleMiddle AgedPrognosisRetrospective Studiescolorectal cancerinflammationneutrophilsoverall survivalprognosis

Identifiers

PMID39376564
PMCPMC11456424

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.