Correlation between clinicopathological indices and expression of cluster of differentiation 24 and cluster of differentiation 44 biomarkers in oral epithelial dysplasia and oral squamous cell carcinoma patients: A follow-up study.

Narges Ghazi, Nasrollah Saghravanian, Kazem Anvari, Majid Mirhashemi, Mohammadhadi Erfanian

Abstract read

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Article in Dental research journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

Role of Stem Cells and Stem Cell Markers in Oral Potentially Malignant Disorders and Malignant Transformation: A Systematic Review.Stem cells international · 2026
Review
Tumor microenvironment-derived IL-32 promotes aggressive phenotypes and stem cell traits in head and neck squamous cell carcinoma.Journal of dental sciences · 2026
Article

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Narges GhaziDepartment of Oral and Maxillofacial Pathology, Oral and Maxillofacial Diseases Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.

Nasrollah SaghravanianDepartment of Oral and Maxillofacial Pathology, Oral and Maxillofacial Diseases Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.

Kazem AnvariCancer Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Majid MirhashemiDepartment of Oral and Maxillofacial Pathology, Oral and Maxillofacial Diseases Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.

Mohammadhadi ErfanianDepartment of Oral and Maxillofacial Pathology, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Oral squamous cell carcinoma (OSCC) is the most common oral cavity cancer and may occur following oral epithelial dysplasia (OED). Cancer stem cells (CSCs) can self-renew and multi-directionally differentiate to promote tumorigenesis with high expression of cluster of differentiation (CD) 24 and CD44 markers. CSCs play a pivotal role in tumor development, drug resistance, and relapse after treatment. We aimed to evaluate the correlation between both marker expressions and clinicopathological indices in OED and OSCC patients. Materials and Methods: In this follow-up study, we could access 37 patients, including 12 OEDs and 25 OSCCs (Grade I: Results: There was no significant difference in the expression of CD24 and CD44 markers between the study groups ( Conclusion: Although more than half of the patients demonstrated high expression of both markers, there was no statistically significant difference between them and clinicopathological indices.

Indexed as

Cluster of differentiation 24cluster of differentiation 44dysplasianeoplastic stem cellssquamous cell carcinoma of head and neck

Identifiers

PMID39376260

PMCPMC11457982

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