Evidence map›Paper›PMID 39376246›Full record

ArticleTherapeutic advances in vaccines and immunotherapy2024

Exploring COVID-19 vaccine adverse events among pregnant women: a cross-sectional study, 2022.

Ahmed A Amer, Samar A Amer, Amerah Badokhon, Sherif M Hammad, Mohamed A Wasfy, Misha Khan, Tahani Ateyah Al-Harbi, Sadah Qamous Alobaid, Georgette Eskander, Amro Abdel-Azeem and 2 more

Abstract read
In one paragraph

Article in Therapeutic advances in vaccines and immunotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ahmed A AmerDepartment of Obstetrics and Gynecology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Samar A AmerDepartment of Community, Environmental and Occupational Medicine, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Amerah BadokhonAdministration of Health Awareness, Ministry of Health Jeddah, Jeddah, Saudi Arabia.
Sherif M HammadFaculty of Medicine, Beni Suef University, Beni Suef, Egypt.
Mohamed A WasfyDepartment of Obstetrics and Gynecology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Misha KhanDepartment of Medicine and Surgery, Liaquat National Hospital and Medical College, Karachi, Pakistan.
Tahani Ateyah Al-HarbiDepartment of Clinical Health Education, Administration of Health Awareness, Ministry of Health, Jeddah, Saudi Arabia.
Sadah Qamous AlobaidDepartment of Clinical Health Education, Administration of Health Awareness, Ministry of Health, Jeddah, Saudi Arabia.
Georgette EskanderDepartment of Biochemistry, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
Amro Abdel-AzeemPopulation Health Management and Research, Riyadh First Health Cluster, Ministry of Health, Riyadh 11564, Saudi Arabia.ORCID https://orcid.org/0000-0001-8607-1536
Abdulmajeed AlshowairVP Community Health Excellence, Riyadh First Health Cluster Ministry of Health, Riyadh, Saudi Arabia.
Mohamed Sh RamadanDepartment of Obstetrics and Gynecology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Clear and trustworthy information is crucial to improving public acceptance of COVID-19 vaccinations, especially among pregnant women. Given the increased risk of severe viral pneumonia in pregnant women, it is critical to foster confidence in the vaccine's safety and understand any potential adverse events (AEs). So, we did this study in Jeddah, Saudi Arabia (SA), from March to May 2022 to compare women who did not get any doses of the COVID-19 vaccine during pregnancy (Group A) to women who did get at least one dose during pregnancy (Group B) regarding (1) the frequency, types, AEs, and management of its AEs of the COVID-19 vaccination; and (2) exploring pregnancy, delivery, and fetus-related complications (e.g., miscarriage, birth defects, and preterm labor). Methods: A cross-sectional study targeted 438 women who gave birth or were pregnant within the previous 8 weeks. Data was collected through face-to-face interviews with skilled nurses in 13 randomly selected primary healthcare facilities, using a validated, well-structured questionnaire that included the Centers for Disease Control (CDC) COVID-19 vaccination-related AEs. We analyzed the collected data using SPSS version 27. Results: Most participants were aged 25 to less than 35 (58.8%), and 287 (61.3%) were university graduates. There was no statistically significant difference among the studied groups regarding demographics. However, women in Group B had a significantly higher rate of abortions, oligohydramnios (24.4%), abnormal placentas (size and location), 103 (42.7%) abnormal fetal growth, 122 (53.7%) problems breastfeeding, blood pressure problems, and more cases of malaise, headaches, chest pain, breathing problems, and sleep problems than women in Group A. After the second and third doses, the confirmed post-vaccination COVID-19 rates in Group B were lower than those in Group A. Conclusion: The COVID-19 vaccine significantly reduces post-vaccination COVID-19. Although COVID-19 vaccine-related AES are prevalent, analgesics and antipyretics effectively treat most of them.

Indexed as

adverse eventsCOVID-19Jeddahpregnancyvaccination

Identifiers

PMID39376246
PMCPMC11457191

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.