Evidence map›Paper›PMID 39375586›Full record

SynthesisBMC medical imaging2024

Artificial intelligence in predicting recurrence after first-line treatment of liver cancer: a systematic review and meta-analysis.

Linyong Wu, Qingfeng Lai, Songhua Li, Shaofeng Wu, Yizhong Li, Ju Huang, Qiuli Zeng, Dayou Wei

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC medical imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Colorectal cancer liver metastases: A radiologic point of view.World journal of gastrointestinal oncology · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Linyong Wu *Department of Medical Ultrasound, Maoming People's Hospital, Maoming, Guangdong Province, 525011, People's Republic of China.
Qingfeng Lai *Second Ward of Nephrology Department, Maoming People's Hospital, Maoming, Guangdong Province, 525011, People's Republic of China.
Songhua LiDepartment of Medical Ultrasound, Maoming People's Hospital, Maoming, Guangdong Province, 525011, People's Republic of China.
Shaofeng WuDepartment of Medical Ultrasound, Maoming People's Hospital, Maoming, Guangdong Province, 525011, People's Republic of China.
Yizhong LiDepartment of Radiology, Maoming People's Hospital, Maoming, Guangdong Province, 525011, People's Republic of China.
Ju HuangDepartment of Radiology, Maoming People's Hospital, Maoming, Guangdong Province, 525011, People's Republic of China.
Qiuli ZengSecond Ward of Nephrology Department, Maoming People's Hospital, Maoming, Guangdong Province, 525011, People's Republic of China.
Dayou WeiDepartment of Medical Ultrasound, Maoming People's Hospital, Maoming, Guangdong Province, 525011, People's Republic of China. weidayoumm@163.com.

Funding

Guangdong Provincial Medical Science and Technology Research Fund Project A2024269Guangdong Yiyang Healthcare Charity Foundation 2023CSM001
6 · The paper itself

Abstract

backgroundThe aim of this study was to conduct a systematic review and meta-analysis to comprehensively evaluate the performance and methodological quality of artificial intelligence (AI) in predicting recurrence after single first-line treatment for liver cancer.

methodsA rigorous and systematic evaluation was conducted on the AI studies related to recurrence after single first-line treatment for liver cancer, retrieved from the PubMed, Embase, Web of Science, Cochrane Library, and CNKI databases. The area under the curve (AUC), sensitivity (SENC), and specificity (SPEC) of each study were extracted for meta-analysis.

resultsSix percutaneous ablation (PA) studies, 16 surgical resection (SR) studies, and 5 transarterial chemoembolization (TACE) studies were included in the meta-analysis for predicting recurrence after hepatocellular carcinoma (HCC) treatment, respectively. Four SR studies and 2 PA studies were included in the meta-analysis for recurrence after intrahepatic cholangiocarcinoma (ICC) and colorectal cancer liver metastasis (CRLM) treatment. The pooled SENC, SEPC, and AUC of AI in predicting recurrence after primary HCC treatment via PA, SR, and TACE were 0.78, 0.90, and 0.92; 0.81, 0.77, and 0.86; and 0.73, 0.79, and 0.79, respectively. The values for ICC treated with SR and CRLM treated with PA were 0.85, 0.71, 0.86 and 0.69, 0.63,0.74, respectively.

conclusionThis systematic review and meta-analysis demonstrates the comprehensive application value of AI in predicting recurrence after a single first-line treatment of liver cancer, with satisfactory results, indicating the clinical translation potential of AI in predicting recurrence after liver cancer treatment.

Indexed as

Artificial IntelligenceCarcinoma, HepatocellularLiver NeoplasmsNeoplasm Recurrence, LocalChemoembolization, TherapeuticCholangiocarcinomaColorectal NeoplasmsHumansSensitivity and SpecificityArtificial intelligenceLiver cancerPercutaneous ablationRecurrenceSurgical resectionTransarterial chemoembolization

Identifiers

PMID39375586
PMCPMC11457388

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.