Evidence map›Paper›PMID 39375527›Full record

SynthesisBone marrow transplantation2025

Non-cryopreserved autologous peripheral blood stem cell transplantation for multiple myeloma and lymphoma in countries with limited resources: practice considerations from the Worldwide Network for Blood and Marrow Transplantation.

Mohamed Amine Bekadja, Dietger Niederwieser, Mohamed A Kharfan-Dabaja, Riad El Fakih, Laurent Garderet, Ibrahim Yakoub-Agha, Hildegard Greinix, Daniel J Weisdorf, Sebastian Galeano, Syed Osman Ahmed and 23 more

Erratum issuedAbstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Bone marrow transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

33 authors.

Mohamed Amine BekadjaEHU 1st November, Oran, Algeria.
Dietger NiederwieserDivision of Hematology and Medical Oncology, University of Leipzig, Leipzig, Germany.ORCID 0000-0002-4737-1103
Mohamed A Kharfan-DabajaDivision of Hematology-Oncology and Blood and Marrow Transplantation and Cellular Therapy Program, Mayo Clinic, Jacksonville, FL, USA. KharfanDabaja.Mohamed@mayo.edu.ORCID 0000-0001-7394-5185
Riad El FakihAdult Hematology, Stem Cell Transplant & Cellular Therapy, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia. relfakih1@kfshrc.edu.sa.
Laurent GarderetCentre de Recherche Saint-Antoine, Sorbonne Université-INSERM, UMR_S 938, Paris, France.
Ibrahim Yakoub-AghaCentre Hospitalier Universitaire de Lille, Université de Lille, Lille, France.ORCID 0000-0003-4524-8782
Hildegard GreinixDivision of Hematology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.ORCID 0000-0002-2780-3300
Daniel J WeisdorfDivision of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, USA.ORCID 0000-0001-8078-8579
Sebastian GaleanoDepartment of Hematology, Hospital Británico, Montevideo, Uruguay.
Syed Osman AhmedAdult Hematology, Stem Cell Transplant & Cellular Therapy, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Christian ChabanonInstitut Paoli-Calmettes, Inserm CBT-1409 & Aix-Marseille Université, Marseille, France.ORCID 0000-0002-3755-4889
Shahrukh K HashmiDivision of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-8914-7927
Annalisa RuggeriSan Raffaele Scientific Institute, Milano, Italy.ORCID 0000-0002-7261-2765
Usama GergisSidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.ORCID 0000-0003-0656-7385
Ali BazarbachiBlood and Marrow Transplantation Program, Department of Internal Medicine, American University of Beirut, Beirut, Lebanon.ORCID 0000-0002-7171-4997
Nada HamadAustralia and New Zealand Transplant and Cellular Therapies (ANZTCT), Department of Haematology, St Vincent's Hospital Sydney, Sydney, NSW, Australia.ORCID 0000-0001-7929-1450
Amal AlbeihanyKing Faisal Specialist Hospital and Research Center, Madinah, Saudi Arabia.
Marcelo PasquiniDivision of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI, USA.ORCID 0000-0003-1579-2293
Amr HanbaliAdult Hematology, Stem Cell Transplant & Cellular Therapy, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Jeff SzerClinical Haematology, Peter MacCallum Cancer Centre and The Royal Melbourne Hospital Melbourne, Melbourne, VIC, Australia.ORCID 0000-0001-6783-2301
Yoshihisa KoderaDepartment of Promotion for Blood and Marrow Transplantation, Aichi Medical University School of Medicine, Nagakute, Japan.
Ambuj KumarDepartment of Internal Medicine Director, Research Methodology and Biostatistics Core, Office of Research Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
Tusneem ElhassanAdult Hematology, Stem Cell Transplant & Cellular Therapy, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
Donal McLornanDepartment of Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.ORCID 0000-0003-1224-091X
Nina WorelDepartment of Transfusion Medicine and Cell Therapy, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-3599-8099
Raffaella GrecoHematology and Bone Marrow Transplantation Unit, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milano, Italy.ORCID 0000-0002-6117-5328
Mohamad MohtyCentre de Recherche Saint-Antoine, Sorbonne Université-INSERM, UMR_S 938, Paris, France.ORCID 0000-0002-7264-808X
Yoshiko AtsutaJapanese Data Center for Hematopoietic Cell Transplantation, Nagakute, Japan.ORCID 0000-0003-4404-2870
Mickey KohSt. George's Hospital and Medical School, London, UK.ORCID 0000-0002-4368-2502
Anna SuredaHematology Department, Institut Català d'Oncologia-Hospitalet, IDIBELL, University of Barcelona, Barcelona, Spain.ORCID 0000-0002-1238-6970
Damiano RondelliDivision of Hematology/Oncology, University of Illinois at Chicago, Chicago, IL, USA.
Mahmoud AljurfAdult Hematology, Stem Cell Transplant & Cellular Therapy, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia. maljurf@kfshrc.edu.sa.ORCID 0000-0003-3942-7370
Walid RasheedAdult Hematology, Stem Cell Transplant & Cellular Therapy, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autologous peripheral blood stem cell (PBSC) transplantation is a standard treatment of multiple myeloma (MM), Hodgkin lymphoma and various subtypes of non-Hodgkin lymphoma. Cryopreservation of hematopoietic stem cells is standard practice that allows time for delivery of conditioning regimen prior to cell infusion. The aim of this Worldwide Network for Blood & Marrow Transplantation (WBMT) work was to assess existing evidence on non-cryopreserved autologous transplants through a systematic review/meta-analysis, to study feasibility and safety of this approach. We searched PubMed, Web of Science and SCOPUS for studies that utilized non-cryopreserved autologous PBSC transplantation. Identified literature was reviewed for information on mobilization, apheresis, preservation and viability, conditioning regimen, engraftment, response, and survival. Results highlight collective experience from 19 transplant centers (1686 patients), that performed autologous transplants using non-cryopreserved PBSCs. The mean of infused CD34+ was 5.6 × 10

Indexed as

LymphomaMultiple MyelomaPeripheral Blood Stem Cell TransplantationTransplantation ConditioningCryopreservationHumansTransplantation, Autologous

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.