Evidence map›Paper›PMID 39375379›Full record

ArticleScientific reports2024

Similarities of metabolomic disturbances in prematurity-associated obstructive lung disease to chronic obstructive pulmonary disease.

Christopher W Course, Philip A Lewis, Sarah J Kotecha, Michael Cousins, Kylie Hart, Kate J Heesom, W John Watkins, Sailesh Kotecha

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Toward precision for bronchopulmonary dysplasia: Moving past current definitions.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christopher W CourseDepartment of Child Health, School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK.
Philip A LewisFaculty of Life Sciences, University of Bristol, Bristol, UK.
Sarah J KotechaDepartment of Child Health, School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK.
Michael CousinsDepartment of Child Health, School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK.
Kylie HartDepartment of Paediatrics, Cardiff and Vale University Health Board, Cardiff, UK.
Kate J HeesomFaculty of Life Sciences, University of Bristol, Bristol, UK.
W John WatkinsDepartment of Child Health, School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK.
Sailesh KotechaDepartment of Child Health, School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK. kotechas@cardiff.ac.uk.

Funding

Medical Research Council MR/M022552/1
6 · The paper itself

Abstract

Prematurity-associated lung disease (PLD) is a long-term consequence of preterm-birth. Since the underlying mechanisms of PLD remain poorly characterised, we compared the urinary metabolome between recently described spirometry phenotypes of PLD. Preterm- and term-born children aged 7-12 years, from the Respiratory Health Outcomes in Neonates (RHiNO) cohort, underwent spirometry and urine collection. The urinary metabolome was analysed by gas chromatography time-of-flight mass spectrometry. Preterm-born children were classified into phenotypes of prematurity-associated obstructive lung disease (POLD, Forced expiratory volume in 1 s (FEV

Indexed as

Infant, PrematureMetabolomeMetabolomicsPulmonary Disease, Chronic ObstructiveChildFemaleForced Expiratory VolumeHumansInfant, NewbornLung Diseases, ObstructiveMalePremature BirthSpirometryFatty acidsGlutathioneMass spectrometryMetabolomicsPrematuritySpirometry

Identifiers

PMID39375379
PMCPMC11458810

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.